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5497 results found

Importance of visual fields for detection of progression in glaucoma

Early detection of progression of glaucoma, and escalating treatment is vital to maintain vision in patients. In this paper from the Early Manifest Glaucoma Trial (EMGT) group they compared the earliest detection of progression in visual fields and monoscopic optic...

Stromal cell alignment in damaged cornea

Stromal keratocytes are responsible for wound healing in the cornea following damage. Keratocytes at the site of injury become activated and differentiate to myofibroblasts which secrete extracellular matrix (ECM) to close the wound, a response mediated by transforming growth factor...

RTP801 as a neuroprotective and axon regenerative treatment

This paper describes the neuroprotective and axon regenerative effects of siRTP801, which is a translatable small-interfering RNA (siRNA) targeting mTOR negative regulator; RTP801, through in-vivo and in-vitro models. In-vivo studies involved an optic nerve crush rat model with intravitreal injections...

Emergency eye care in the UK: the way forward?

In this paper the authors highlight issues pertaining to the growing number of patients presenting to the emergency eye services in the UK. Data collection involved literature review, telephone surveys and email correspondence (n=142). Ninety-one lead clinicians responded and a...

Systemic screening in adnexal lymphoma

This is a retrospective review of 119 patients diagnosed with ocular adnexal lymphoma, 85 of whom had primary adnexal disease and 34 had previously been diagnosed with lymphoma outside the ocular adnexa. Sixty-eight of the primary and 24 of the...

The dynamic nature of orbital cavernous haemangiomas

This paper seeks to address the question of how much do orbital cavernous haemangiomas actually change over time, and if there are any identifiable factors which can predict which lesions will grow and which will remain stable. In particular, if...

Inhibiting high-risk corneal allografts

The cornea is an immune privileged site and as such corneal transplants are very successful. However, in situations where this privilege is lost the failure rises substantially. To combat rejection inhibition of the immune responses depends on steroids and other...

Should intravitreal steroids be used in the initial treatment of post-op endophthalmitis?

Endophthalmitis following cataract surgery is one of the most feared complications, and can have significant impact on the visual outcomes of patients. The role of steroids in the management of endopthalmitis is controversial. The aim of this paper was to...

Developing a training model to strengthen diabetic retinopathy screening through a VISION 2020 LINK in India

I. Development of LINK Partnership A VISION 2020 LINK India was established by signing a Memorandum of Understanding (MoU) in 2018 between the Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India, Frimley Health NHS Foundation Trust and...

Phacogeddon

A trainee shortly to rotate to my firm was unhappy at the fact that she had only one phaco list in her timetable. She was a final year trainee with more than five hundred cataract extractions to her name so...

COVID-19 and Ophthalmology: RCOphth, ICEH and COECSA joint webinar

The Royal College of Ophthalmology of Eastern, Central and Southern Africa (COECSA) and the Royal College of Ophthalmologists (the Royal College) have had a successful VISION 2020 LINK partnership for over 12 years. The partnership was established by the VISION...

Prediction errors of formulas in optical biometers

This study was conducted retrospectively in a private practice setting. Nine formulas were compared for prediction error (postoperative spherical equivalent (SE) minus, predicted SE calculated by each formula), using two optical biometers (Lenstar – optical low coherence reflectometry (OLCR) and...