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Genetic therapy gives infants life-changing improvements in sight

24 February 2025 | genetics, gene therapy, Moorfields, paediatrics, research, new, AIPL1, Leber Congenital Amaurosis
Four young children have gained life-changing improvements in sight following treatment with a pioneering new genetic medicine through Moorfields Eye Hospital and UCL Institute of Ophthalmology, with the support of MeiraGTx. The children were born with a severe impairment to...

Comparison of corneal deformation parameters in keratoconic and normal eyes

1 February 2018 | | EYE - Cataract, EYE - Refractive
This study set out to compare biomechanical properties between normal and keratoconic eyes. It was a retrospective study evaluating 89 eyes (47 normal, 42 keratoconic) and a validation arm of 72 eyes (33 normal, 39 keratoconic) using a high speed...

Capsular tension rings to reduce refractive shift

1 June 2018 | | EYE - Cataract, EYE - Refractive
The study group aimed to determine whether the use of a capsular tension ring (CTR) can increase refractive stability in patients with implantation of two different trifocal intraocular lenses. This was a prospective, consecutive series of eyes which underwent refractive...

Comparison of two interferon gamma release assays (IGRA) for tuberculous uveitis

1 December 2014 | | EYE - Vitreo-Retinal
In this prospective cohort study the authors compared QuantiFERON-TB Gold In-Tube and T-SPOT.TB to evaluate their diagnostic accuracy. They enrolled 120 consecutive new uveitis presentations over a two year period in a tertiary centre. The majority were Chinese (61.3%), followed...

Treatment for cause of sudden sight loss now available through the NHS in England

24 September 2025 | LHON, NICE, vision Loss, mitochondrial disease, NHS England
The National Institute for Health and Care Excellence (NICE) has approved a treatment for Leber Hereditary Optic Neuropathy (LHON), called Idebenone (Raxone), in those aged 12 and above who are affected by the condition. LHON is a rare mitochondrial genetic...

NICE approves treatment for cause of sudden sight loss

15 October 2025 | genetics, neuro-ophthalmology, drugs, new treatments, mitochondrial
The National Institute for Health and Care Excellence (NICE) has approved a treatment for Leber Hereditary Optic Neuropathy (LHON), called Idebenone (Raxone), in those aged 12 and above who are affected by the condition. LHON is a rare mitochondrial genetic...

Real world data of post-IVT endophthalmitis, from a nurse-delivered intravitreal injection service

3 April 2023 | | EYE - General
Introduction Intravitreal injection of neutralising anti-vascular endothelial growth factor (VEGF) antibody was licenced more than a decade ago, and over the years there has been proportionate increase in the number of intravitreal injections [1]. Injection of a therapeutic agent through...

Under pressure: a tool to aid the 
non-ophthalmic practitioner in the timely management of acute angle closure

1 April 2017 | | EYE - Glaucoma, EYE - Neuro-ophthalmology
Acute angle closure is a true ophthalmic emergency that mandates timely diagnosis and treatment. The priority in initial management is to lower the intraocular pressure in an expeditious matter using medical treatments. The risk of irreversible glaucomatous optic neuropathy is...

Robotic assisted orbital surgery (RAOS) – a novel approach to orbital malignancy surgery

3 June 2024 | | EYE - Orbit, EYE - Oculoplastic, EYE - General
Robotic technology in ENT surgery has been used in certain areas of head and neck cancer care but, in this article, we hear of an exciting development from the team at Guy’s & St Thomas’. Advances in surgical robotic technology...

How to examine the visual system Part 1: visual acuity, visual fields and eye movements

1 June 2014 | | EYE - Vitreo-Retinal
Asking candidates to perform an examination of the visual system, either as part of a full cranial nerve exam or as an individual entity, is a common station in practical examinations during medical school. It is important to practise for...

RCOphth to host digital event on COVID-19 recovery

25 August 2020
The RCOphth will be running its first ever virtual conference with lectures and discussions on restarting services, theatre pathways, the impact on training, home testing, digital innovations and the physical effects of the virus on the eye.

The IAPB searches for its 2021 Eye Health Heroes

21 August 2021
The International Agency for the Prevention of Blindness has launched its annual development programme to celebrate and nurture young and upcoming talent in the eye health sector.