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Teprotumumab for chronic TED

This retrospective case series looks at the use of teprotumumab in nine patients with thyroid eye disease (TED) of clinical activity score ≤one and >nine months duration, in an American cohort. Current European guidelines have suggested the use of teprotumumab...

Outcomes from evisceration with primary implant in 1800 patients

This is a retrospective analysis of 1800 patients who had evisceration with orbital implant between 2013-2019. As the largest published series on this topic, the authors are able to give relatable real-world data on complications following surgery. They use a...

Therapeutic options for advanced cutaneous basal (BCC) and squamous cell carcinomas (SCC)

This article discusses the use of topical and systemic therapy in the management of advanced periocular tumours. It focuses on those that have gained United States Food and Drug Administration approval; namely imiquimod, vismodegib, sonidegib, pembrolizumab and cemiplimab. Imiquimod is...

Ocular findings in children with myasthenia

This is a retrospective audit of paediatric myasthenic patients presenting to Great Ormond Street (GOSH) between January 2016 and January 2020. During this period there were 49 children, including 27 with juvenile myasthenia (JMG) and the rest as congenital myasthenia...

Differentiating orbital cellulitis from non-specific orbital inflammation

This is a retrospective study looking at whether common laboratory investigations can help differentiate between orbital cellulitis (OC) and non-specific orbital inflammation (NSOI). NSOI is a diagnosis of exclusion following negative investigations for systemic diseases such as IgG4-related disease, granulomatosis...

Female participation at the AAO conference

This study sought to understand whether female participation among paediatric ophthalmologists at the American Academy of Ophthalmology (AAO) annual meeting resembles the sex distribution of the field as well as whether the Covid-19 pandemic significantly affected female involvement. From 2018–2022,...

Treatment of vertical diplopia in the reading position

This paper describes the use of slab-off prisms for the treatment of vertical diplopia in the reading position. The following data were collected: main symptom complaint, visual acuity, refractive error, binocular vision including sensory fusion and stereoacuity, alternating cover test...

Oxymetazoline hydrochloride for improved symmetry in Graves’ disease

Oxymetazoline hydrochloride 0.1% ophthalmic solution has Food & Drug Administration (FDA) approval for use in involution ptosis. It is an alpha 1 agonist and partial alpha 2 agonist that stimulates Muller’s muscle to lift the lid. The authors of this...

Laissez-faire approach for medial canthus tumours

This is a retrospective comparative case series of patients who underwent reconstruction of a medial canthal defect using laissez-faire approach (LFS), or a full-thickness skin graft (FTSG). The surgical options were discussed with the patient and the treatment decision was...