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Types of nystagmus and associations in a large international database for nystagmus

The authors aimed to characterise a large international cohort of children with nystagmus. Data were taken from a prospective database which was started in 2010. Up to 2020, this contained 1774 patients with nystagmus from 38 US states and 30...

Preparing to start as a consultant

I was just coming to the end of a fantastic glaucoma fellowship at Moorfields, during which Samad Ansari had been a colleague and friend, and soon to start as a consultant in Oxford where Rebecca Turner is Clinical Director, and...

Air toxicity on retinal pigment epithelium

This study investigated the potential toxic effects of air on primary human retinal pigment epithelial (RPE) cells in vitro. Clinically during pars plana vitrectomy air is used as either a temporary tamponade during air-fluid exchange or mixed with gas to...

The effect of everolimus on retinal pigment epithelium and proliferative vitreo-retinopathy

The principal cells involved in proliferative vitreo-retinopathy (PVR) are retinal pigment epithelial cells (RPE). Everolimus is a drug used in renal cell carcinoma which targets and inhibits a key regulatory protein in cancer (mTOR). In this study, the authors investigated...

Understanding the pachychoroid disease spectrum

This article provides a comprehensive review of the pachychoroid disease spectrum, a group of chorioretinal disorders characterised by abnormal choroidal thickening and various pathological changes in the choroid, retinal pigment epithelium, and retina. It also highlights the controversies and knowledge...

Unconscious bias (part 2)

Does unconscious bias exist, and does training help to reduce discriminatory behaviour? Clare Inkster questions her role as a trainer. I read Gwyn Williams’ Learning Curve article on this topic a few months ago with interest, and as someone who...

GDPR, email and private practice

A new set of data protection regulations became law in the EU (including the UK) in May 2018. General Data Protection Regulation (GDPR) replaces the 1988 Data Protection Act. The regulation brings new rights and expectations about how our personal...

Embryology in clinical practice

The fascinating world of embryology is both beautiful and practical. It is a home video of our evolutionary history through the ages from the single cell through to the life aquatic, the development of gut, limbs and brain, and most...

International Women’s Day 2025: In Conversation With Dr Michelle Le Cheminant

Women make up 70% of the global health and social workforce but hold only 25% of leadership roles. In ophthalmology, women represent just 25-30% of ophthalmologists. Research shows that hospitals with increased female surgeons and anesthetists have lower odds of...

Demyelinating optic neuropathy

Introduction Optic neuritis (ON) is an inflammatory process affecting the optic nerve. After glaucoma, it is the most common optic neuropathy affecting patients under the age of 50. The usual presentation of typical ON is unilateral subacute loss of vision...

How good does my vision have to be to drive this thing? Visual standards for various occupations

We can all picture that moment in clinic: you are about to tell someone that they’re no longer legally able to drive, ready to deploy our ‘breaking bad news’ techniques. For some patients this may have been expected, or they...

Toxic nutritional optic neuropathy (TON)

Toxic optic neuropathy are a group of conditions manifested by reduction of visual functions secondary to damage to the anterior visual pathways from exposure to a toxin. The implicated toxin could be work-based, food or drink related, or iatrogenic medication....