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Association between diabetes mellitus and dry eye disease

Diabetes mellitus (DM) is currently one of the most prevalent chronic diseases in the United States. It is estimated that 12.3% of Americans suffer from DM. In this study the authors compare between dry eye and diabetes mellitus among a...

We are all Hadiza

When I worked as a registrar at Newport many years ago I remember a no-nonsense corneal consultant railing about the way the tragic case of Lucie Linforth was being reported in the media. Lucie was a toddler taken into a...

Characteristics of central serous chorioretinopathy by age

The authors present a cohort study of 326 patients with simple central serous chorioretinopathy (CSC) according to the classification system laid down by Chhablani, et al. in 2020. Genotyping for two variants of the CFH gene rs800292 and rs1329428 was...

Mid-term evaluation of the new Glaukos iStent

This is a prospective non-randomised interventional study to assess the efficacy and safety of the Glaukos GTS-400 iStent combined with cataract surgery. The patients enrolled in the study had cataract and primary open angle glaucoma, pseudoexfoliation glaucoma or ocular hypertension....

Likelihood of developing multiple sclerosis after optic neuritis diagnosis

Optic neuritis (ON) is a relatively common cause of acute optic neuropathy in young patients which often presents as the first sign of multiple sclerosis (MS). There is a lack of evidence around the factors that are associated with the...

The disease burden of AMD

In this multi-centre, prospective, observational, time and motion study the authors assessed the time burden of managing wet AMD for doctors, staff, patients and caregivers in the USA. The study spanned the period from March 2011 to August 2012, and...

Detection of antiranibizumab antibodies in exudative AMD

In this study the authors aimed to detect immune response to ranibizumab treatment in wet age-related macular degeneration (AMD). An ELISA was employed to quantify the anti-ranibizumab titre which was compared against the control anti-abciximab titre. Titres of anti-ranibizumab antibodies...

Long-term use of botulinum toxin for hemifacial spasm and blepharospasm

The authors conducted a retrospective review of clinical / procedure documentation for consecutive blepharospasm (BEB) and hemifacial spasm (HFS) patients undergoing treatment with onabotulinum toxin A (Botox) in one clinic setting over the past 20 years. They report on the...

Bitemporal hemianopsia as a result of ethambutol toxicity

The authors present six cases of visual loss in patients treated with ethambutol for mycobacterium avium complex, including four patients with bitemporal hemianopsia. Two additional patients were undergoing glaucoma monitoring and developed visual field defects with ethambutol treatment, which recovered...

“I can see fine. Why do I need my eyes tested?”

Are routine eye examinations really necessary? The author asks whether frequent appointments in low-risk patients with normal results are actually cost-effective. It’s recommended that most people should get their eyes tested every two years.” [1] This message is widely publicised...

All systems go for Oriel - final approval granted to make new centre a reality

Plans for Oriel, a new state-of-the-art eye care, research and education centre, have been given the green light.

PRPF31-related retinitis pigmentosa and asymptomatic carriers

The authors present a study of 21 patients with variants in the PRPF31 gene classified as pathogenic or likely pathogenic. These variants are caused by autosomal dominant retinitis pigmentosa (RP-11). Between January 2020 and November 2021 patients underwent tests of...