Search

Correlation between structural and functional status of optic nerve and retina in multiple sclerosis

Multiple sclerosis (MS) involves autoimmune inflammatory demyelination and axonal degeneration in the central nervous system. Investigation of the retina and optic nerve head (ONH) is an ideal way to visualise this demyelination. This study investigates the functional and structural properties...

Use of the RAPDx device to evaluate efficacy of treatment in patients with optic nerve disease

The RAPDx objectively determines the RAPD magnitude by alternately presenting light stimuli to each eye and deriving amplitude and latency scores. The authors of this paper evaluated the amplitude and latency scores from the RAPDx together with other ophthalmic investigations...

Differences in elastometry of cornea and optic nerve head in both eyes of patients with NAION

Non-arteritic anterior ischaemic optic neuropathy (NAION) is an important cause of visual loss in the middle aged and elderly population. This prospective cross-sectional study investigates the biomechanical properties of optic nerve head (ONH) and cornea in both eyes of patients...

Case report review of children with septo-optic dysplasia and optic nerve hypoplasia

Septo-optic dysplasia (SOD) and optic nerve hypoplasia (ONH) cause congenital visual impairment. Their aetiology is mostly unknown. The authors aim was to investigate the prevalence of specified ophthalmological features in patients with these disorders. These features included impaired visual acuity,...

Natural history of optic nerve head drusen in a paediatric population

A retrospective case notes review is presented focusing on children diagnosed with optic nerve head drusen over an eight-year period. Inclusion criteria included cases coded for optic nerve head drusen and / or pseudopapilledema. The aim of the study was...

Using modified staging criteria to determine optic nerve invasion in retinoblastoma

This paper reports the use of a modified staging criteria for optic nerve invasion in extraocular retinoblastoma and its correlation with treatment outcomes in 21 patients. The average age at presentation was 41 months (7–120) and there were 14 unilateral...

Changes, with increasing age of children, in optic nerve head parameters and retinal thickness

In this study, the authors aimed to compare stereometric parameters of the optic disc and inner retinal layer thickness (peripapillary retinal nerve fibre layer (pRNFL) and ganglion cell inner plexiform layer (GCIPL)) at two time points in the same children...

Optic nerve head perfusion response to reduced blood pressure and increased intraocular pressure

The purpose of this prospective study was to test the hypothesis that blood flow autoregulation in the optic nerve head has less reserve to maintain normal blood flow where there is a blood pressure induced decrease in ocular perfusion pressure...