You searched for "age"
Brolucizumab in age-related macular degeneration, HAWK Study
3 October 2023
| Kurt Spiteri Cornish
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EYE - Vitreo-Retinal
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Neovascular age-related macular degeneration, aflibercept, anti-vascular endothelial growth factor therapy, brolucizumab, commercial formulation
The aim of the study was to collect additional data on efficacy and safety of brolucizumab 6mg intended for commercialization in age-related macular degeneration (AMD) (with an increase in pH and decrease in polysorbate concentration). The HAWK Study was a...
Update on emerging therapies for age-related macular degeneration
4 December 2023
| Rod McNeil
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EYE - Vitreo-Retinal
The 23rd European Society of Retina Specialists (EURETINA) Congress, held in Amsterdam, the Netherlands, provided a timely update on anti-complement therapy for geographic atrophy and emerging investigational therapies for neovascular age-related macular degeneration. Anti-complement therapy for geographic atrophy Geographic atrophy...
Age-related macular degeneration in elderly persons in Germany
1 April 2020
| Patty Mopamboli Mboli
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EYE - Vitreo-Retinal
The authors present the findings of a cross-sectional study in 11 seniors’ community centres. Eleven community centres were screened with a total of 281 participants. A third of participants with gradable images were in normal retinal health (32%).The most common...
Comparison of outcomes of bilateral cataract surgery across different age groups
The authors present a retrospective records review of children who had bilateral cataract surgery between the ages of two and seven years of age over a 23-year period. Children with other ocular pathology and prior surgery were excluded. A minimum...Pegcetacoplan: A breakthrough treatment for dry age-related macular degeneration?
Age-related macular degeneration (AMD) is a degenerative condition affecting the macula, the part of the retina responsible for central vision. It is characterised by the presence of drusen and retinal pigment epithelium (RPE) abnormalities in the absence of other macular...
Association between serum 25-hydroxyvitamin D levels and age-related cataracts
Cataractogenesis occurs as a result of ageing, smoking, exposure to UV radiation and genetic predisposition. Antioxidants can reduce the cataract risk as found in animal models and humans and vitamin D is one of them. This epidemiological study based in...
At what age do children start to negatively judge ptosis?
The authors present a cohort study to assess for the presence of peer bias against ptosis. Recruitment took place in nursery and primary schools, of children aged three to six-years-old. An exclusion criterion was the presence of a visible ophthalmic...
Complement factor B polymorphism and the phenotype of early age-related macular degeneration
1 August 2014
| Huw Edward Oliphant
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EYE - Vitreo-Retinal
The relationship between complement factor H (CFH) and age-related macular degeneration (AMD) is very well known, but other genetic polymorphisms relating to AMD are more poorly understood. This study was designed to investigate the relationship between complement factor B (CFB)...
Exposure to atomic bomb radiation and age-related macular degeneration in later life
1 October 2015
| Wai Siene Ng
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EYE - Vitreo-Retinal
This paper is one of the outcomes of the Adult Health Study; a cohort study of the atomic bomb survivors of Hiroshima-Nagasaki in Japan. It investigates the proposed association between pasty radiation exposure early in life and the presence of...
Effect of blue-light filtering intraocular lenses on age-related macular degeneration
7 April 2021
| Anna Song
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EYE - Vitreo-Retinal
This is a retrospective cohort study evaluating whether blue-light filtering (BLF) intraocular lenses (IOL) offer prophylaxis for neovascular age-related macular degeneration (nAMD). The study included 11,397 eyes of 11,397 patients with a mean age of 75.4 ±8.3 years that underwent...
Does the length of the school day have a role in age of myopia onset?
The authors prospectively collected the refractive data of myopic adults attending recruiting dispensing optician or ophthalmologist sites. Participants were recruited consecutively, giving verbal informed consent. Sites included a mix of urban and rural areas across eight sites. The following data...Simulating the visual impairment symptoms of age-related macular degeneration in virtual reality
5 June 2023
| Cameron R M Wilson, Ian Underwood, Baljean Dhillon (Prof)
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EYE - Vitreo-Retinal
A new virtual reality application visually simulates age-related macular degeneration and demonstrates its progression over time including some Charles Bonnet syndrome hallucinations. Introduction Age-related macular degeneration (AMD) is the leading cause of blindness in developed countries with the prevalence of...
