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Complement factor B polymorphism and the phenotype of early age-related macular degeneration

The relationship between complement factor H (CFH) and age-related macular degeneration (AMD) is very well known, but other genetic polymorphisms relating to AMD are more poorly understood. This study was designed to investigate the relationship between complement factor B (CFB)...

Is laser refractive surgery safe for patients taking isotretinoin?

This multicentre, retrospective, interventional case series assesses the outcomes of laser in situ keratomileusis (LASIK) and photorefractive keratectomy (PRK) in 113 patients taking isotretinoin between January 2003 and September 2017. Isotretinoin is contraindicated for LASIK and PRK and patients are...

The rarebit vision test for macular conditions

Rarebit testing is used to measure low degrees of neuro-visual damage and is available for free on the internet. It consists of a fixed bright light dot presented on a black background. During testing it is presented briefly at different...

IO over action surgery

This study aimed to compare the effectiveness of the two surgical methods on the correction of inferior oblique over action (IOOA). This was a retrospective study of 99 eyes of 56 patients; 47 myectomy and 52 anterior transposition procedures. Mean...

Van Herick Plus

This a consecutive cross-sectional study of 95 phakic patients over the age of 40-years-old. By applying a short, vertical slit beam, the inferior angle at the scleral-limbal junction at 6 o’clock position was evaluated, photographed and assessed by a ratio...

Visual outcomes after surgery for primary RRD in era of microincision vitrectomy

This is a prospective, multicentre, nationwide study between 2016 and 2017, to investigate the preoperative ocular factors, surgical techniques (pars plana vitrectomy (PPV) or scleral buckling (SB), or combined procedures) for rhegmatogenous retinal detachment (RRD) and postoperative best corrected visual...

Human leucocyte antigen association of patients with Stevens-Johnson syndrome in Han Chinese

This is a retrospective study of the human leucocyte antigen (HLA) polymorphism pattern of cold medicine-induced patients with Stevens-Johnson syndrome and toxic epidermal necrolysis (SJS/TEN) (n=33) and 98 control patients recruited between 2016-2017 in Taiwan. Severe ocular complications (SOC) was...

All eyes on Twiggy as she fronts new campaign warning us: don’t lose focus of your eye health

Dame Twiggy Lawson fronts a new public awareness campaign focused on eye health, as cases of macular disease increase with our ageing population.

The role of inflammation in the pathophysiology of DMO

Diabetic macular oedema (DMO) is a major cause of visual loss in diabetes, with a complex multifactorial pathogenesis. In the UK alone it is estimated that there are nearly 2.5 million diabetic patients aged over 12 years. Approximately 65,000 of...

Diagnoses of dry eye disease double within a year

Over a third of Britons haven’t had an eye test within the last two years, while one in five have not had an eye test due to financial struggles.

The management of retinal vein occlusions: a summary

Retinal vein occlusions (RVO) are the most common cause of visual loss from retinal vascular disease second to diabetic retinopathy. Vision is lost due to ischaemia, macular oedema and / or haemorrhage which ultimately effects a patient’s quality of life...

In conversation with Andrena McElvanney (President, MCLOSA)

We spoke to Andrena about MCLOSA's annual meeting this November, key developments in cornea and external eye disease, and plans for the association’s 30th anniversary. Andrena McElvanney (top, second from right) and the OSI council members. The Medical Contact Lens...