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Association between colour vision impairment and amyotrophic lateral sclerosis (ALS)
The purpose of this study is to test the hypothesis that colour vision impairment is associated with amyotrophic lateral sclerosis (ALS). Abnormalities of the inner and intermediate retinal structures in patients with ALS have been described using optical coherence tomography...
Acetazolamide and CMO
The authors set out to analyse the effect of acetazolamide therapy on inflammatory cystoid macular oedema (CMO) as defined by change in central macular subfield thickness (CST), as well as its effect on visual acuity. A retrospective chart review was...
Genetic cause for idiopathic foveal hypoplasia
The authors present a small cohort study of 19 patients with idiopathic foveal hypoplasia diagnosed based on optical coherence tomography (OCT) features. Peripheral blood samples from all 19 patients underwent next-generation sequencing and 33 genes known to be involved in...Welcome from Guest Editor Evelyn Mensah
I loved attending RCOphth Annual Congress face-to-face in Glasgow this year. How wonderful it was to see old friends and meet new after two pandemic years. At Congress I chaired the session on ‘Racism in the NHS’ with ‘three professors’...An interview with a glaucoma consultant: Insights for aspiring trainees
In this article, Resident Doctor Chi Kit Yan sits down with Consultant Glaucoma Specialist Salman Sadiq and explores the daily life of a glaucoma specialist, the pros and cons of the role, how trainees can prepare for this subspecialty, and...Vitreomacular traction: natural course vs. vitrectomy vs. ocriplasmin
Over time, the vitreous gel completely separates from the retina in a process known as a posterior vitreous detachment (PVD). In some instances, however, the vitreous does not detach entirely and remains adherent to the macula. The term vitreomacular traction...
OCTA FAZ measurements in vein occlusion
Previous studies have confirmed that foveal avascular zone (FAZ) enlargement is correlated with visual acuity impairment in patients with retinal vein occlusion (RVO). This current study aimed to evaluate the OCT angiography parameters: the area of FAZ, foveal and parafoveal...
Corneal lenticule allotransplant
This animal study looked at corneal lenticule allograft transplantation in rabbits. Seven rabbits underwent small incision lenticule extraction (SMILE) procedures, where their stromal lenticules were extracted and transplanted fresh into pre-prepared corneal stromal pockets of seven recipient eyes. Animals were...
Retinal ganglion cell loss in diabetes and diabetic retinopathy
The aim of this observational case control study was to evaluate the association of diabetes and diabetic retinopathy (DR) with retinal ganglion cell loss. Cases were Chinese patients with type 2 diabetes with and without DR, aged 40-80 years. Eligible...
Using OCT to screen and monitor Alzheimer’s disease
Alzheimer’s disease (AD) is a neurodegenerative illness characterised by progressive decline in cognitive function. AD is the main cause of dementia worldwide. Over recent years researchers have strived to find biomarkers to diagnose AD, particularly in the early stages of...
High myopia macular thickness
The purpose of this study was to compare macular thickness and volume in 15 highly myopic (>-6D) young children with 11 age-matched controls (-2 to +4D refractive errors) using Stratus third generation OCT. Mean spherical equivalent was -9.42 ±2.81D for...
