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Influence of FLEx and SMILE on corneal nerve density and ocular surface

This was a prospective study designed to compare the influence of femtosecond lenticule extraction (FLEx) and small incision lenticule extraction (SMILE) on the corneal nerve density and ocular surface for myopic correction. Thirty patients underwent bilateral lenticule extraction. One eye...

Visual performance of new multifocal IOL

Multifocal IOLs (MIOLs) keep evolving to try and get the best outcome in terms of vision and reduction of side-effects. This prospective interventional study was carried out on 34 eyes of 17 patients (11 women (65%) and six men (35%))...

Injection frequency and anatomic outcomes following conversion to Aflibercept in neovascular AMD patients

This is a retrospective study of patients with neovascular age-related macular degeneration (AMD) treated with intravitreal Lucentis and / or Avastin who were switched to aflibercept (Eylea). This study was carried out by the Casey Eye Institute retinal clinics, between...

Intravitreal aflibercept for retinal angiomatous proliferation (RAP)

In this prospective study the authors present the visual and anatomical outcome of patients with RAP lesions who were treated with intravitreal aflibercept. The study cohort of 46 patients reached study completion at week 96. They were all Caucasians, with...

Rebound phenomenon after IVT triamcinolone acetonide for macular oedema

In this retrospective study, the authors report the rebound phenomenon after intravitreal triamcinolone acetonide (IVTA) injection for macular oedema secondary to diabetic retinopathy (DR) and central (CRVO) or branch retinal vein occlusion (BRVO). The incidence of a rebound phenomenon was...

IVTA for diabetic macular edema and macular edema secondary to retinal vein occlusion: a meta-analysis

This meta-analysis aimed to compare the safety and efficacy of different doses of intravitreal triamcinolone acetonide (IVTA) for diabetic macular oedema (DME) and macular oedema (ME) secondary to retinal vein occlusion (RVO). A systematic literature search for randomised controlled trials...

Alternative diagnosis in cases of poor response to amblyopia therapy

The aim of this study was to assess the prevalence of coexistent ocular pathology and identify / describe the factors that contribute to undiagnosed alternate diagnosis and / or co-existent pathology at initial presentation in patients referred as potentially amblyopic....

Outcomes of office and home-based training vs part-time occlusion for intermittent exotropia management

This study aimed to compare patch therapy with non-surgical treatment options for intermittent exotropia (IXT) using a synoptophore with/without simultaneous active orthoptic treatment and a maintenance treatment using computer-based gaming software. This 3-group trial recruited 72 patients. Intervention 1 (N=24)...

Isolated trochlear (fourth cranial) nerve palsy in an Asian population

The authors report on 35 consecutive new cases of isolated fourth cranial nerve palsy seen over a period of six months in one neuro-ophthalmology clinic in Southeast Asia, with emphasis on their aetiology and management. We report on 35 patients...

Optic nerve swelling – your survival guide (part 1)

Assessment of optic nerve appearance and functions is a daily routine in neuro-ophthalmology. Following a recent high profile court case there has been a significant increase in the amount of referral to ophthalmology departments to assess the optic nerve and...

An update on inherited retinal disorders (part 2): Approaches to therapy for IRDs

Part 1 of this topic can be found here There are currently no proven cures for inherited retinal disease (IRD). However, multiple avenues of research are being investigated to better understand disease mechanisms and trial potential therapies that may slow...

Andean Medical Mission in action 2025

Dear friends and supporters, What 12 months it has been for the Andean Medical Mission! Thanks to your encouragement and generosity, we’ve been able to continue our work to eliminate avoidable blindness in the Beni region of Bolivia — and...