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Aflibercept, bevacizumab or ranibizumab for diabetic macular oedema

Macular oedema (MO) is a leading cause of visual impairment in patients with diabetic retinopathy. Whilst laser photocoagulation therapy has been the proven treatment for decades, studies over the last five years have also established a role for anti-VEGF agents...

Cataract surgery in patients with retinitis pigmentosa

Retinitis pigmentosa (RP) is the commonest inherited cause of retinal degeneration. Posterior subcapsular cataract (PSC) develops in 41% to 90% of these patients by age 40 years. In this retrospective study, the authors have evaluated surgical outcomes in patients with...

Injection of methotrexate into silicone oil-filled eyes for grade C PVR

Methotrexate (MTX) is an antineoplastic antimetabolite with immunosuppressant properties. Folate antagonism is known to contribute to the antiproliferative effects of MTX, and release of adenosine from cells and inhibition of polyamines may explain its anti-inflammatory effects. These activities contribute to...

Corneal crosslinking in pellucid marginal degeneration

Fourteen studies were included in this first review examining the use of corneal-crosslinking (CXL) to treat pellucid marginal degeneration (PMD). PMD is a bilateral, non-inflammatory corneal thinning disorder characterised by inferior peripheral corneal thinning 1-3mm from the limbus in the...

Oral Ibuprofen reduces early bleb failure in high risk trabeculectomy

In this retrospective cohort study, 288 eyes of 273 patients (mean ±SD age: 68.56 ±10.47 y; 32.60% females) with primary glaucoma who underwent trabeculectomy / phacotrabeculectomy at the Singapore National Eye Centre between April 2020 and April 2021 with a...

Binocular single vision (BSV)

Introduction In this article I will try to summarise some of the definitions, tests and assessments performed in the strabismus clinic to assess patient binocular potential. This is a key feature of strabismus assessment, especially in adults, and it will...

Can thou lyse this? A national study of emergency canthotomy and cantholysis

Eighty-two-year old Janet Smith woke up on the floor. Had she been unconscious? Her head hurt. It was the middle of the night, but in the darkness she suddenly wasn’t sure whether she could see out of her right eye....

Deadline approaching for Edinburgh scholarship applications

The University of Edinburgh has opened applications for scholarships to its two online courses, the MSc in Primary Care Ophthalmology and the ChM in Clinical Ophthalmology.

Longitudinal changes in axial length in high myopia

This is a prospective, longitudinal, observational single centre study between May 2011 and September 2018, to determine the changes in the axial length (AL) longitudinally in patients with high myopia without other conformational abnormalities. Patients were divided into two groups:...

‘The Way Forward’ champions clinicians as architects of patient-centred service redesign

The demographic time bomb poses the dilemma of how more healthcare can be delivered to the UK’s ageing population without commensurate growth in resources. The Way Forward Project provides a robust resource for clinical centres to better identify and implement...

Simulated ocular surgery

See also Simulated ocular surgery - strabismus surgery and Simulated ocular surgery: pars plana vitrectomy and scleral buckling surgery This is the first of a series of articles that will have three aims. Firstly, to demonstrate why simulated ocular surgery...

New developments

To reflect the fact that this column consists of not just web links, but also mobile and general technology content we have changed the name from Internet to ‘Tech Review’. In keeping with the title, this issue includes a mixture...