You searched for "pigment"
A review of neuro and retinal imaging findings in Alzheimer’s disease
The authors present a systematic review with the aim of assessing the relationship between retinal and cerebral changes in Alzheimer’s disease (AD), mild cognitive impairment and pre-clinical AD. A total of 23 articles met the inclusion criteria of the review,...
Progression of macular atrophy in Stargardt disease
The authors present a study of a cohort of patients with genetically proven ABCA4 gene mutation related Stargardt disease. They aimed to quantify the effect of lesion location and topography on disease progression using fundus autofluorescence imaging. One hundred and...
Clinical predictors of proliferative sickle cell retinopathy
Sickle Cell Disease (SCD) is an inherited disorder resulting in production of Haemoglobin S (HbS), which aggregates in conditions of hypoxia, acidosis or hyperosmolarity. This leads to vascular stasis, thrombosis and ischaemia. The authors present a cross-sectional study (45 consecutive...
Transsynaptic retrograde degeneration linked to homonymous visual field loss after stroke
centre, of individuals identified with homonymous visual field loss post ischaemic stroke. Exclusion criteria were bilateral ischaemia, anterior / pregeniculate visual pathway affected and other pathology with the potential to effect visual fields. The following were extracted from the medical...
Case presentation: seizures as a presenting sign of idiopathic intracranial hypertension
Idiopathic intracranial hypertension (IIH) is a syndrome of isolated elevated intracranial pressure of unknown cause. Neurological examination in IIH is typically normal except for papilloedema and possible cranial nerve six palsy, although rare, atypical symptoms and signs can occur. With...
EOM enlargement in carotid cavernous fistulas
This study evaluates the radiological patterns of extraocular muscle enlargement and proptosis in carotid cavernous fistulas (CCF). At least one muscle was enlarged in 27.5% of cases. The inferior rectus was most commonly enlarged, followed by the medial rectus. Proptosis...
Updated staging of LCHADD retinopathy
The authors present their proposal for an updated staging system for Long-Chain 3-Hydroxyacyl-CoA Dehydrogenase (LCHAD) deficiency retinopathy. This is a rare mitochondrial disease due to deficiency of the long chain fatty acid oxidation pathway. Forty patients who were part of...
Stargardt disease in a Turkish cohort
The authors present a study of 27 Turkish patients who were seen in a single centre over a five-year period. All patients had macular optical coherence tomography (OCT), colour fundus photography and 30-2 Humphery visual fields performed, along with clinical...
Should we work together to identify congenital nasolacrimal duct obstruction and otitis media?
The authors present a retrospective medical notes review. The aim of the study was to establish how common tympanostomy tube (T-tube) insertion is in children needing probe and intubation (P&I) for congenital nasolacrimal duct obstruction (CNLDO). All cases of CNLDO...
What characteristics are linked with adolescent blindness and severe visual impairment
The authors present a retrospective cohort analysis which aimed to characterise the risk factors for adolescents being blind or severely visually impaired. The publicly available National Survey of Drug Use and Health (NSDUH) was used as the data source and...
PAX6 methylation and myopia
The authors present a case control study of 41 adolescents (age 12–14) with myopia and 39 age- and sex-matched non-myopic controls. The myopic patients were sub-divided into mild, moderate and severe myopia subgroups. DNA was extracted from peripheral blood samples...
