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Is optic disc drusen a risk factor in young patients with anterior ischaemic optic neuropathy?

This retrospective cross-section multicentre study reviewed 65 patients all younger than 50-years-old with non-arteritic anterior optic neuropathy (NA-AION) between April 2017 and March 2019. The purpose of this study was to investigate if there was a link between Optic Disc...

Detailed overview of diplopia causes and outcomes for a single tertiary care centre

The purpose of this study was to study the aetiology, progression and outcome in patients with binocular diplopia presenting to the ophthalmology department of a tertiary care centre in India. The study had a prospective observational design where all patients...

Using optical coherence tomography angiography to detect MoyaMoya vasculopathy

Moyamoya (MM) disease is a chronic cerebrovascular disease that can lead to progressive stenosis of the terminal portions of the internal carotid arteries and their proximal branches. The authors carried out a cross-sectional cohort study to investigate vascular changes in...

Profile of paediatric cranial nerve palsies

The purpose of this study was to retrospectively assess the aetiology of paediatric ocular cranial nerve palsies (CNP) using neuro-ophthalmic data from three hospitals. The study included 1263 patients aged <18 years suspected of having strabismus, from January 1999 to...

Silicone oil (SOT) versus gas (GT) tamponade for primary rhegmatogenous retinal detachment treated successfully with a propensity score analysis

This is a retrospective, nationwide, multicentre study with retinal detachment (RD) in the Japan-RD Registry between 2016 to 2017. The primary outcome was the estimated mean difference of postoperative cerebral vascular accident (CVA) in six months and a propensity score...

Environmental variations in endophthalmitis

In this retrospective cohort study, the authors looked at seasonal and environmental variations in 171 endophthalmitis cases out of 423,297 intravitreal injections. The incidence of this complication was not correlated to monthly snowfall, rainfall, or average temperature. There was no...

Outcomes of combined medial and laser treatment for advanced Coat’s disease

In this study, the anatomical and visual outcomes of paediatric patients with advanced stage 3+ Coat’s disease are reported. Patients were treated with a combination of intravitreal ranibizumab, laser photocoagulation and methyl prednisolone acetate. This was a retrospective review of...

The risk factors associated with isolated microvascular third nerve palsy

The authors used the Rochester Epidemiology Project for this retrospective case review of third nerve palsy. Inclusion criteria was adults >18 years, with new onset isolated microvascular third nerve palsy diagnosed within a 36-month period, with recovery or significant improvement,...

Neurogenic palsy due to COVID-19

The authors aimed to identify cases of neurogenic palsy in the presence of Covid-19 and document the patient characteristics, type of palsy and possible aetiologies. Case reports and case series were included in the search. Twenty-three articles were included with...

Use of oral fluorescein angiography in a paediatric population

The authors report a retrospective records review of all patients who received an oral ultrawide fluorescein angiography (FA) over a 42-month period at a single children’s hospital. Data were extracted from the records including indication for FA, adverse events, pauses...

Anatomical and functional outcomes following switching from aflibercept to ranibizumab in NARMD

This is a six-month, prospective, single-arm study in the UK and Germany. A total of 100 patients were enrolled (one in the primary failure group, 99 in the suboptimal treatment response group), treated three-monthly intravitreal ranibizumab injections (0.5mg), and then...

Submacular haemorrhage associated with nAMD: A meta-analysis and meta-regression on use of tPA and anti-VEGFs

The aim of this study was to evaluate the efficacy of a combination of tPA and anti-VEGF in the treatment of submacular haemorrhage (SMH) associated with neovascular age-related macular degeneration (nAMD). A systematic review meta-analysis following PRISMA guidelines, focusing on...