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Brn3b neuroprotective effect in rat glaucoma model

An adeno-associated virus-directed overexpression of the Brn3b protein in hypothesised to confer neuroprotective effects in this paper. This is ultimately tested in a well-accepted rat glaucoma model (Morrison’s model: saline injection into episcleral veins of rat eyes with a force...

RPE use similar pathway to regulatory T cells to inhibit immune response

Retinal pigment epithelial (RPE) cells form an important part of the blood-retinal barrier that protects the neuronal cells responsible for sight. RPE cells are involved in innate and adaptive immune responses via expression of surface molecules and release of cytokines....

Patient-reported outcomes in oculoplastic surgery

This is an important if somewhat difficult to grasp article which tries to formally address the subject of patient-reported outcomes in oculofacial surgery. The authors have conducted an extensive review of the literature searching for instruments (questionnaires) which have been...

A paradigm shift in the way we approach cataract surgery

Cataract surgery is the most common elective surgical procedure in the UK [1], with in the region of 350,000 cases being conducted each year. With an ageing population, this figure will only continue to rise over time. Cataract surgery is...

Comic leaflets: an innovative method of patient education

Nowadays almost everyone has been exposed to comics, especially during childhood. In a way, this is a natural form of progression from children’s story books, which also contain words and pictures. This exposure has helped us to develop the graphic...

Study finds telemedicine improves care for children with eye cancer

Orbis announces new research that finds telemedicine can improve care for children with retinoblastoma, a form of childhood cancer that can lead to blindness. The study, published in JCO Global Oncology, is the first to show that virtual mentor-mentee relationships...

Improving cataract efficiency: insights and learnings from expert practitioners

An evening surgical meeting sponsored by Théa Pharmaceuticals Ltd brought together leading experts to share insights and experience on practice strategies to enhance the efficiency of cataract surgery. Streamlining patient flow to optimise capacity and efficiency Qasim Mansoor, Consultant Ophthalmic...

Orbital rhabdomyosarcoma treatment characteristics

The aim of this study was to review the clinical presentation, management, local and systemic outcomes of 14 orbital rhabdomyosarcoma (OR) cases with the focus on the role of surgery as treatment. The mean age at presentation was eight years...

Consecutive exotropia overcorrection

The authors evaluate the postoperative outcomes of unilateral medial rectus recession surgery for the treatment of persisting consecutive esotropia >10PD more than six months in 16 patients (three adults and 13 children) who were overcorrected after initial surgery for intermittent...

Syndromic V-pattern management

The authors document their experience in the management of four cases of Crouzon syndrome and review the anatomical extraocular muscle anomalies noted during surgery. Horizontal strabismus surgery varied in each of the four cases according to individual extraocular muscle abnormalities...

Early diagnosis of pituitary apoplexy using combined MRI findings

The author presents a literature review searching the terms ‘pituitary ring sign’ and ‘sphenoid sinus mucosal thickening’ in the context of pituitary apoplexy from 1990 until the present day. These two findings are both magnetic resonance imaging (MRI) signs of...

Reported cases of hemifield slide phenomenon

This article reports three cases of hemifield slide, a phenomenon whereby there is an inability to stabilise and fuse visual hemifields. It occurs with heteronymous visual field loss and is thought to result from the loss of corresponding retinal points....