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Guide to Gaining Approval for a Clinical Study
This article focuses on gaining approval for clinical research involving NHS patients, although the principles can be applied to other types of research. The intention is to give an overview of the requirements for setting up a research study, but...
Inflammation and microvascular changes in diabetic retinopathy
Studies have shown that neurodegeneration and inflammation in the retina start early in diabetic retinopathy (DR) and can be present before the latter is clinically evident. The aim of this retrospective review of 99 diabetic patients was to evaluate retinal...Glaucoma patients can monitor and treat their own IOP!
Simerdip Kaur takes a look at the latest ophthalmology-related stories in the news. Headline: Glaucoma patients can monitor and treat their own IOP! It is well known that poorly controlled intraocular pressure (IOP) is a leading risk factor for glaucoma...Obituary: Sohan Singh Hayreh (1927 - 2022)
Sohan would have been 95 on 6 November this year, but due to complications of COVID-19, he passed away on 29 September.
Using lumbar puncture as a diagnostic tool of IIH when the presentation is typical
The authors present the findings of a retrospective observational chart review across three neuro-ophthalmology clinics. Databases at each clinic were searched using inclusion criteria based on established diagnostic criteria for idiopathic intracranial hypertension (IIH). Cases with missing data, atypical findings...
Postoperative diplopia test with BT for inferior oblique overaction
The authors evaluate a novel assessment of botulinum toxin (BT) injection into the inferior oblique (IO) as a postoperative test in those with secondary IO overaction. This was a retrospective review of 23 injections for 18 patients using 1.25U of...27th Nottingham Eye Symposium and Research Meeting
A unique opportunity for the dissemination and discussion of cutting-edge basic science and clinical ophthalmic research. Conference Chair: Ms. Dalia Said The 27th Nottingham Eye Symposium & Research Meeting anticipates a delegation of approx. 150 ophthalmologists from around the UK...
Role of amniotic membrane in ocular surface disease
This comprehensive review traces the use of amniotic membrane in ophthalmology from its first documented application in ocular surface reconstruction in the 1940s through the improved processing and preservation methods that drove renewed clinical interest in the late 20th century....
Air toxicity on retinal pigment epithelium
This study investigated the potential toxic effects of air on primary human retinal pigment epithelial (RPE) cells in vitro. Clinically during pars plana vitrectomy air is used as either a temporary tamponade during air-fluid exchange or mixed with gas to...
Retinal changes prior to hydroxychloroquine toxicity
In this retrospective longitudinal study, the authors examined changes in retinal layer thickness in patients taking hydroxychloroquine without evidence of retinopathy. Patients were drawn from a hydroxychloroquine screening clinic and required at least two OCT scans, at least one year...
