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RaScaL Study
The RaScaL study was a six month, single-centre, controlled, prospective phase I/II study in which subjects with diabetic macular oedema (DME) and associated peripheral nonperfusion on ultrawide-field fluorescein angiography (UWFA) were randomised to: (1) study arm: ranibizumab (0.5 mg) injection...New NHS study highlights ways to help patients with painful, slow-healing corneal wounds recover sooner
Teams at Queen Victoria Hospital NHS Foundation Trust (QVH) and Maidstone and Tunbridge Wells NHS Trust (MTW) have published new findings highlighting how long and demanding treatment can be for people with persistent corneal epithelial defects and how a clinic-based...A new observation point: updating the nomenclature and classification with OCT
The evolution of ophthalmic imaging technologies has been particularly rapid over the last few years. The author provides an update of the current terms for common signs and pathologies observed using optical coherence tomography. My experience as an ophthalmic technician,...Thousands of retired staff return to the NHS
More than a third of nurses who retired two years ago had returned to practice 12 months later, according to new NHS England figures.PREVIEW: Join us at the TROPHY Ophthalmic Conference 2025!
The highly anticipated TROPHY Ophthalmic Conference returns this year with an impressive lineup of experts, cutting-edge technological advances, and engaging discussions that promise to strengthen the field of ophthalmology. The TROPHY Ophthalmic Conference is Trent Ophthalmic Society's flagship event, provides...The Syrian Ophthalmologists Initiative (SOI): A lifeline to the future of ophthalmology in Syria
Syria, a nation with over 22 million people, has faced more than a decade of conflict that has severely impacted its healthcare infrastructure. Medical training has become fragmented, with many doctors lacking access to structured postgraduate education and essential clinical...
A phase 3 randomised trial of nicotinamide for skin cancer chemoprevention
To B3, or not to B3? That was the question asked in this controlled trial in which the authors were able to show that oral nicotinamide (vitamin B3) is able to reduce further skin cancer development in high risk patients....
A randomised, controlled trial of oral propranolol in infantile haemangioma
Since its use was first reported in the New England Journal in 2008, propranolol has become the preferred treatment for infantile haemangiomas. However, there is no consensus as to the optimum dose or duration of treatment and there is a...
Inhibiting high-risk corneal allografts
The cornea is an immune privileged site and as such corneal transplants are very successful. However, in situations where this privilege is lost the failure rises substantially. To combat rejection inhibition of the immune responses depends on steroids and other...
Anatomical and functional outcomes following switching from aflibercept to ranibizumab in NARMD
This is a six-month, prospective, single-arm study in the UK and Germany. A total of 100 patients were enrolled (one in the primary failure group, 99 in the suboptimal treatment response group), treated three-monthly intravitreal ranibizumab injections (0.5mg), and then...
