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Topical cyclosporine A 0.05% for recurrent anterior uveitis
This is a retrospective case-crossover study conducted by reviewing medical charts of patients treated for recurrent anterior uveitis between 2002 and 2011 at the Kellogg Eye Centre by one cornea specialist. The demographics, episodes of anterior uveitis, severity of episodes...
RTP801 as a neuroprotective and axon regenerative treatment
This paper describes the neuroprotective and axon regenerative effects of siRTP801, which is a translatable small-interfering RNA (siRNA) targeting mTOR negative regulator; RTP801, through in-vivo and in-vitro models. In-vivo studies involved an optic nerve crush rat model with intravitreal injections...
Allergic eyelid dermatitis
This is a retrospective 12 year review of 61 patients diagnosed with periocular allergic dermatitis. The average age was 66 years, with 74% being female. The commonest indications for referral were epiphora, ectropion and blepharitis; and the main symptoms were...
Reduction of postoperative bruising and swelling
This is a review of 27 patients undergoing periocular surgery who postoperatively applied hydrogel pads impregnated with Arnica montana and Ledum palustre (Ocumend, Cearna inc., Chicago). The pads were used continuously for the first two postoperative days, changing them every...
Facilitators and barriers to conducting research
A survey of clinicians and researchers across the UK was conducted to identify barriers to research and potential solutions. The authors extracted details of studies listed on the UKCRN database that involved paediatric ophthalmology with recruitment of children. An e-survey...
Micropulse vs. continuous wave trans scleral diode cyclophotocoagulation in refractory glaucoma
Continuous wave cyclophotocoagulation (CWCPC) delivers continuous high intensity energy to the ciliary body in an attempt to reduce aqueous secretion and hence lower IOP. It is often used as a treatment of last resort due to the potential side-effects of...
Effect of topical diclofenac on postoperative PRK pain: RCT
A major disadvantage of excimer laser photorefractive keratectomy (PRK) is pain and discomfort after the surgery, which is thought to be due to damage to corneal sensory nerve fibres or local release of inflammatory substances. Pain only resolves once corneal...
Superior oblique muscle tuck
The authors investigate the efficacy and safety of isolated superior oblique tucking in patients with congenital superior oblique palsy. The study includes 21 cases: eight females and 13 males aged 2-34 years. All had obvious superior oblique under action and...
Glaucoma prevalence in sleep apnoea
Obstructive sleep apnoea (OSA) is a disorder characterised by brief interruptions of breathing during sleep and results from complete or partial collapse of the pharyngeal airway. This study investigated the prevalence and progression of glaucoma in 39 patients receiving treatment...
Imaging and histological relationship of orbital Schwannomas
This is a retrospective review of 15 patients with orbital Schwannomas comparing the radiological characteristics, in particular the signal intensity on MRI, with the histological sub-types of the tumours. Five patients had MRI imaging alone, three had CT alone and...
Meta-analysis of HLA B27 associated acute anterior uveitis
A literature-based meta-analysis was carried out to look at the various clinical features associated with HLA- B27 acute anterior uveitis (AAU). After an extensive search of literature for HLA B27 uveitis was conducted, 735 results were obtained. Twenty-nine articles were...
