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Therapeutic options for advanced cutaneous basal (BCC) and squamous cell carcinomas (SCC)

This article discusses the use of topical and systemic therapy in the management of advanced periocular tumours. It focuses on those that have gained United States Food and Drug Administration approval; namely imiquimod, vismodegib, sonidegib, pembrolizumab and cemiplimab. Imiquimod is...

Subperiosteal abscess management in adolescents and adults

This is a retrospective study looking at the clinical and treatment profiles of patients with orbital subperiosteal abscess (SPA) in an adolescent and adult population. SPA is rarer in this age group compared to a paediatric population (less than nine-years-old)...

Narrative review of idiopathic intracranial hypertension in children / adolescents

Idiopathic intracranial hypertension (IIH) affects both children and adults. Whilst the majority of IIH is mainly seen amongst adults, it also affects children. There are currently no clinical trials in IIH for those who are adolescents or children. The aims...

Agreeing terminology for non-classic visual field abnormalities

The authors present a prospective survey of neuro-ophthalmologists. The survey comprised of 10 visual fields. The selection of visual fields for the survey aimed for variety and excluded classic neuro-ophthalmology visual field defects, e.g. hemianopia, nasal step. The survey was...

Surgical management and review of congenital inferior rectus dysgenesis

Three cases are presented of congenital inferior rectus (IR) dysgenesis causing hypertropia. Case 1 was a two-year-old female with intermittent vertical strabismus of 20PD and -2 limitation on depression, worse in abduction. MRI imaging showed a hypoplastic IR. Following surgery,...

Brolucizumab in age-related macular degeneration, HAWK Study

The aim of the study was to collect additional data on efficacy and safety of brolucizumab 6mg intended for commercialization in age-related macular degeneration (AMD) (with an increase in pH and decrease in polysorbate concentration). The HAWK Study was a...

Changing operating room practices: the effect on postoperative endophthalmitis rates following cataract surgery

This is a retrospective clinical registry study from India of 85,552 cataract surgery patients; group 1 (56,551 patients from January-March 2020) and group 2 (29,011 patients from May-August 2020). Group 1’s patients were ungowned, surgical gloves were disinfected but not...

Multidrug-resistant keratitis: challenging yet manageable

This is a retrospective review of all patients’ records from a tertiary referral centre in India from January 2018 to December 2019, who had corneal scrapings for direct smear and culture sensitivity. Those cases where the organisms were diagnosed to...

Macular measurements for amblyopic eyes

This study aimed to evaluate the macular parameters including foveal avascular zone (FAV) size and vessel density in amblyopia vs fellow eyes. The study included 23 unilateral amblyopia children (9.86 ±3.12 years; 52.2% female) and non-amblyopia control eyes (8.67 ±2.06...

Disc-fovea angle measurements for objective cyclotorsion review

The author measured the disc-fovea angle (DFA) in 249 healthy people (81 male, 168 female) as part of a retrospective study of 44 to 70-year-old adults. These were grouped as (1) aged 44 / 45 years, (2) aged 59-70 years,...

Ocular motility parameters in phakic and pseudophakic older people

The aim of this study was to compare the extent of phoria, strabismus and convergence of pseudophakic vs phakic people in an elderly population. The study was part of the Tehran Geriatric Eye Study (TGES). Of 3791 invitees, 3310 participated...

Case reports of neuro-visual consequences of mild COVID-19 in children

Neuro-visual involvement has been reported in numerous patients with severe SARS-CoV-2 disease, mainly among adult patients. In children, such involvement has been reported in rare cases, often in those presenting with severe forms of COVID-19. The aim of this work...