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Opening the AI ‘black box’ for glaucoma

Artificial intelligence (AI) models show great promise for glaucoma detection using retinal images, but their ‘black box’ nature is a major barrier to clinical adoption. Clinicians are often hesitant to trust a diagnosis without understanding its reasoning. This paper provides...

Low-dose bimatoprost/timolol gel: a new fixed-combination option

This phase III international randomised trial evaluated the efficacy and safety of a new low concentration bimatoprost/timolol eye gel (bimatoprost 0.01%/timolol 0.1%). It was compared with the conventional higher-strength fixed combination eye drops (bimatoprost 0.03%/timolol 0.5%) in patients with open-angle...

Identification of potential social determinants which may impact on idiopathic intracranial hypertension

The authors analysed cross-sectional data with the aim of exploring the social determinants of idiopathic intracranial hypertension (IIH). The data was obtained from the National Institute of Health (NIH) All of Us research programme (version 6 – May 2018 to...

Motor vehicle accident-related eye trauma trends in the United States

The authors present a large retrospective epidemiological study analysing motor vehicle accident-associated eye injuries presenting to US emergency departments between 2000 and 2020. Using a national injury surveillance database (NEISS-AIP), they examined incidence trends, patient demographics and injury patterns over...

OCT changes after occlusion therapy in amblyopic and fellow eyes

This study compared optical coherence tomography (OCT) data of fellow and amblyopic eyes, and reported OCT changes after long-term electronically monitored occlusion therapy. The study recruited 30 patients with mean age of 16.7 ±11.2 years (range 5.1–44.7 years): 53% males....