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My Top Five: Promising gene therapies for ocular conditions
Gene therapy, a pivotal advancement in modern medicine, particularly shines in ophthalmology. By targeting defective genes with engineered vectors, this approach promises significant strides in treating inherited retinal diseases. This article reviews the top five gene therapies in late-stage trials,...
Essentials of OCT in Ocular Disease
Sir Isaac Newton was the first to establish the technique of low coherence white light interferometry. Following on from this, the principle of laser interferometry as an imaging modality for retina was applied by David Huang and his associates in...Nano-ophthalmology paves a new path in the future of eyecare
Introduction The treatments of ocular conditions in the field of ophthalmology varies from topical to surgical procedures. The field of nanotechnology is one of the fast-growing fields of medicine, which plays an important role in turning the impossibilities of the...
Three years of experience with quantiferon-TB Gold Testing in patients with uveitis
Quantiferon-TB Gold is a new alternative to the tuberculin skin test that utilises synthetic peptides representing M. tuberculosis antigens ESAT-6, CFP-10, TB7.7 and upon incubation with whole blood IFN-γ is released from pre-sensitised T cells and can be measured by...The ABC tragedies: Part one
“In the midst of tragedy, we start the comedy” – Agatha Christie, The ABC Murders. Throughout a career in medicine, we are often faced with tragedy. One of the coping mechanisms is to use humour to navigate the mini everyday...
Environmental variations in endophthalmitis
In this retrospective cohort study, the authors looked at seasonal and environmental variations in 171 endophthalmitis cases out of 423,297 intravitreal injections. The incidence of this complication was not correlated to monthly snowfall, rainfall, or average temperature. There was no...
Surgical technique combining vertical transposition and horizontal plication for mixed deviations
A retrospective case series, assessed adult cases with horizontal and vertical strabismus who had undergone unilateral vertical transposition of the horizontal rectus muscles during a recession-plication over a three-year period. A single surgeon performed all 15 procedures. Postoperative measurements were...
Optical coherence tomography angiography usability in measuring iris vasculature in strabismus surgery
The purpose of this study was to investigate the use of optical coherence tomography angiography (OCTA) as a screening tool for anterior segment ischemia (ASI) in strabismus surgery. Optical coherence tomography angiography measurements were taken in 18 subjects. Twelve were...
Using a tumour registry to investigate optic nerve gliomas
This study is a retrospective comparative analysis. Patients with optic nerve glioma and pilocytic astrocytoma were identified through the Surveillance, Epidemiology and End Results (SEER) cancer registry covering a 42-year period using standardised codes. The following data was extracted: basic...
