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British Journal of Ophthalmology cover image.

IAC vs. IVC chemotherapy for RB

1 April 2018 | | EYE - Paediatrics, EYE - Strabismus
This a single centre retrospective review of consecutive patients between 1997 and 2014, of all sporadic unilateral retinoblastoma (RB) group D cases, treated with combined intravenous chemotherapy (IVC) and focal treatments (1997- 2008), or intra-arterial chemotherapy (IAC) treatment (2008 to...
Pediatric Ophthalmology & Strabismus journal cover

Germline mutation risk in solitary unilateral retinoblastoma

5 August 2022 | | EYE - Paediatrics, EYE - Strabismus
This study aimed to determine the true risk for germline mutation in a child presenting with solitary unilateral RB and whether this risk differs by age at presentation. This was a retrospective review of 482 cases from 1972-2020. Age groups...
British Journal of Ophthalmology cover image.

Ten-year experience with intracameral chemotherapy for aqueous seeding in retinoblastoma: long-term efficacy, safety and toxicity

3 June 2024 | | EYE - Pathology, EYE - Oncology
This is a retrospective review of all consecutive patients with primary (n=4) or secondary non-iatrogenic (n=16) aqueous seeding (AS) treated by intracameral chemotherapy (ICC) in Lausanne between 2011 and 2020 with a minimum follow-up of one year. Aqueous seeding control...
JAAPOS journal cover image.

Difference in retinoblastoma phenotypes based on maternal or paternal inheritance

30 June 2025 | | EYE - Paediatrics, EYE - Strabismus
The aim of this study was to explore the difference in presentation of retinoblastoma between paternal and maternal inheritance. A retrospective medical records review methodology was employed. Records of individuals diagnosed with a retinoblastoma with at least one symptomatic family...

Blind and partially sighted actors star in charity films aimed at getting people to think #BeforeYouAsk

1 November 2023 | RNIB, charity, short films, media, #BeforeYouAsk, Vivienne Francis
Leading sight loss charity the Royal National Institute of Blind People (RNIB) has released a series of humorous, yet challenging, #BeforeYouAsk short films as part of its See the Person, Not the Sight Loss campaign which aims to raise awareness of and dispel misconceptions about sight loss.

Uveal melanoma

3 August 2023 | | EYE - Pathology, EYE - Oncology, EYE - Imaging
Uveal melanoma is the most common primary intraocular tumour. However, they are still rare, with an incidence of 2-8 per million [1]. The presence of a choroidal naevus is a risk factor for uveal melanoma [1]. Patients with choroidal lesions...

Money never sleeps

5 April 2022 | | EYE - Vitreo-Retinal, EYE - General
“I want you to deal with your problems by becoming rich” As declared by Jordan Belfort in a motivational speech to his staff in the film Wolf of Wall Street (2013). Unfortunately, medicine as a career does not lead to...

An unusual presentation of sarcoidosis

1 October 2021 | | EYE - Vitreo-Retinal, EYE - Imaging, EYE - Neuro-ophthalmology, EYE - General
*Equally contributing co-first authors. Case report A 45-year-old man presented to his local optometrist with a three-week history of severe intermittent left eye pain with associated blurred vision and tenderness around his left temple. Two days prior, he developed weakness...

Designing ophthalmology services Part 2: How do we address the queues for a clinic?

1 April 2020 | | EYE - General
The first of this three-part series showed how systems engineering can be used to correctly diagnose and address the causes of delays in a clinic. This second article describes how to design a more productive system that meets the new...

The results of the last survey Jun22

1 June 2022 | | EYE - Cataract, EYE - Vitreo-Retinal, EYE - General
Thank you once more for your time in answering the latest survey. The first question relates to the number of staff required for a routine cataract list. There was a big variance in practice. Some of us are luckier than...

Bridging the gap – Supporting our patients across the primary / secondary care divide

1 June 2017 | EYE - General
Providing the best care for patients is surely a fundamental goal for all healthcare professionals. When waiting-times are long and getting longer, clinics are full, colleagues are off with stress-related illness and patients are complaining, is it possible to still...

How to diagnose and treat Acanthamoeba keratitis

1 February 2019 | | EYE - Cornea, EYE - General
Corneal ulceration caused by Acanthamoeba is on the rise, and recent publications indicate an outbreak in the UK over the last few years [1]. Since Acanthamoeba keratitis often presents with atypical features, diagnosis from slit-lamp examination alone can often be...