You searched for "regenerative"
A revolution in modern genetic testing for the clinical management of ocular disease
1 August 2016
| Jane Ashworth, Chris Lloyd (Prof), Graeme Black
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EYE - Cataract, EYE - Pathology, EYE - Vitreo-Retinal
Recent years have seen a huge increase in our understanding of the genetic factors underlying a wide variety of eye diseases. This has included common conditions such as glaucoma and age-related macular degeneration, as well as those conditions which have...
Outcomes of treated adult-onset ET
This study describes a large cohort of 248 patients with adult onset esotropia (ET) due to a range of causes and details preoperative characteristics, operative procedures and surgical outcomes. Mean age at diagnosis was 52 years. Diagnoses included cranial nerve...RPE tears after intravitreal Lucentis
1 February 2017
| Saruban Pasu
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EYE - Vitreo-Retinal
The current hypothesis regarding retinal pigment epithelium (RPE) tears is the contraction and fibrosis in choroidal neovascularisation (CNV) tissue after anti-VEGF therapy can induce rips in the overlying RPE. This South Korean study aimed to identify the association between RPE...
Long-term outcomes of intravitreal ranibizumab for neovascular AMD
This is a single centre prospective study for the long-term, whole population ‘real-world’ clinical outcomes of ranibizumab therapy in treatment-naïve patients for neovascular age-related macular degeneration (AMD). This study recorded: demographics, Early Treatment Diabetic Retinopathy Study visual acuity (ETDRS VA)...Efficacy and safety of intravitreal aflibercept injection in wet age-related macular degeneration
1 June 2015
| Jonathan Chan
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EYE - Vitreo-Retinal
This is a sub-group study of double masked review of patients randomised to different dosages and treatment frequency compared between aflibercept and ranibizumab treatment. This is to evaluate the efficacy and safety of intravitreal aflibercept (IVT-AFL) in Japanese patients with...
Injection frequency and anatomic outcomes following conversion to Aflibercept in neovascular AMD patients
1 December 2014
| Jonathan Chan
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EYE - Vitreo-Retinal
This is a retrospective study of patients with neovascular age-related macular degeneration (AMD) treated with intravitreal Lucentis and / or Avastin who were switched to aflibercept (Eylea). This study was carried out by the Casey Eye Institute retinal clinics, between...
Incidence and risk factors of ocular hypertension following PPV and SOI
1 December 2018
| Sofia Rokerya
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EYE - Vitreo-Retinal
In this prospective, interventional study the authors evaluated the risk factors for elevated intraocular pressure (IOP) after pars plana vitrectomy (PPV) with silicone oil injection (SOI). This study included 254 eyes of 254 patients, with a mean age of 55.33...
Acanthamoeba ability to adhere to different contact lenses
This study tested ability of Acanthamoeba lugdunensis trophozoites to adhere to silicon hydrogel contact lenses (SHCL) and how this is influenced by different multipurpose contact lens solutions (MPS). Three generations of SHCL were tested: first generation – Air Optix, second...Glaucoma medications and ocular surface disease
3 August 2023
| Su Young
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EYE - Glaucoma
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Drug allergy, OSD, drug toxicity, drug-induced cicatricial keratitis, dry eye, glaucoma medications, ocular surface disease
This literature review examined ocular surface disease (OSD) associated with glaucoma medication. The authors examined the prevalence of features and management guidelines glaucoma medication associated OSD. Fifty-eight articles published within the past five years are included in this review and...
PD-1 and PD-L1 in exenteration specimens
This is an immunohistochemical study looking at variation in the expression of the programmed death-1 receptor (PD-1) and the programmed cell death ligand-1 (PD-L1), comparing cutaneous malignancies which invaded the orbit with uncomplicated nodular basal cell carcinomas. The authors retrospectively...Is exenteration helpful in invasive fungal sinusitis?
1 February 2019
| Claire Howard
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EYE - Neuro-ophthalmology
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Invasive fungal sinusitis, orbital exenteration, posterior ischaemic optic neuropathy
Invasive fungal sinusitis is a potentially lethal disease that causes painful orbital apex syndrome with ophthalmoplegia and visual loss. The mechanism of ophthalmoplegia and visual loss is not clear, and neither is the role of radical surgery-orbital exenteration. The authors...