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The effect of everolimus on retinal pigment epithelium and proliferative vitreo-retinopathy
The principal cells involved in proliferative vitreo-retinopathy (PVR) are retinal pigment epithelial cells (RPE). Everolimus is a drug used in renal cell carcinoma which targets and inhibits a key regulatory protein in cancer (mTOR). In this study, the authors investigated...
Enzymatic clearance of anterior chamber infiltrate in uveitis
Aqueous humour (AH) which fills the anterior chamber (AC) of the eye provides nutrients to the cornea and the lens. Clearance of cellular and particular matter from AH is necessary for good visual acuity. In part this is achieved by...The ophthalmologist’s elbow: a potentially painful point of contact
Three months ago I leant, in the customary manner, on the box of my indirect lens at the slit lamp to examine a patient’s fundus. An acute and severe pain in the tip of my elbow immediately interrupted me. I...Headaches in ophthalmology (part 2)
Ophthalmologists see a large number of patients with headaches or facial pain in the ophthalmic outpatient clinics or in emergency clinics. Over two articles, I will discuss several causes of headaches, ocular manifestations and proposed management and referral options. It...The Worshipful Company of Spectacle Makers rewards early career research
The Worshipful Company of Spectacle Makers (WCSM) this week announced the winners of its annual bronze medal award competitions for vision research. Both the winning submissions demonstrated models for earlier diagnosis of significant eye disease and have the capacity to...
Ocular neuromyotonia
The authors report a cohort of ten patients (nine female) with ocular neuromyotonia (ONM) for clinical signs and symptoms, treatment methods and outcome. Six had affected vertical muscles including superior oblique, inferior rectus and superior rectus. Four had affected lateral...What you learn after performing 10,000 cataracts
What do you do when the anterior chamber shallows, or the zonules give way? How do you handle the stubborn epinuclear plate? Raymond Radford shares the benefit of his experience when dealing with tricky cataract surgery. Firstly, you realise you...
Stereo distance in XT
The test distance effect on stereoacuity was explored in a population with intermittent exotropia along with use of two types of stereograms with crossed and uncrossed disparity. At near and distance distances, the median for both disparities was 60”; 79%...
Medial rectus recession in Grave’s orbitopathy
The purpose of this retrospective study was to analyse the surgical effect / success rate of recession of the medial rectus in 90 patients with horizontal diplopia. Mean age was 52.5 ±9.4 years. Of that 24% had unilateral medial rectus...
Strabismus in high myopia
The authors report the occurrence of exotropia-hypotropia complex in 15 cases of high myopia. The mean age at presentation was 23.5 years (10-35 years). Only two patients had high bilateral myopia. The mean axial length of the deviating eye was...
Horizontal angles in Brown’s syndrome
The purpose of this study was to determine the incidence of horizontal strabismus needing surgical management in Brown’s syndrome. This was a retrospective review of 19 eyes (eight right and 11 left) of 16 patients (seven male and nine female)....
