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Post hoc analysis of the CANTREAT randomised trial

1 December 2023 | | EYE - Vitreo-Retinal | Age-related macular degeneration, Randomized clinical trial, Ranibizumab, Treat-and-extend
CANTREAT, a Canadian multicentre two-year randomised trial compares treat and extend treatment (T&E) relative to the monthly administration of Ranibizumab in nAMD. Two-hundred and eighty-five treatment-naïve patients with nAMD were randomised to receive either a once-monthly dosing or T&E regimen...

Patients use their own blood to treat dry eye symptoms

1 April 2020 | | EYE - Cornea, EYE - General
Simerdip Kaur takes a look at the latest ophthalmology-related news stories and asks which are based on facts and which are ‘fake news’? Headline: Patients use their own blood to treat dry eye symptoms Grossman first described the technique of...

Macula re-attachment following intravitreal ranibizumab in rhegmatogenous retinal detachment

1 February 2015 | | EYE - Vitreo-Retinal, EYE - General
Ranibizumab (Lucentis) is a vascular endothelial growth factor inhibitor (anti-VEGF) used for treatment of choroidal neovascular membrane [1]. We report a case where macula off inferior rhegmatogenous retinal detachment was misdiagnosed as wet age-related macular degeneration (AMD) and three intravitreal...

Fusarium keratitis in a patient with alcohol dependence

1 April 2014 | | EYE - Cornea, EYE - Imaging, EYE - General
Treatment of fungal keratitis secondary to the Fusarium species remains a challenge. Although relatively more common in warmer climates, this corneal infection is rare in the UK. Most cases have been reported in farmers and are often preceded by trauma....

25 years of OCT

1 December 2016 | | EYE - Vitreo-Retinal, EYE - Imaging
David Huang first described optical coherence tomography (OCT) in 1991, in his seminal paper on the subject in Science. This method developed the work of others on ophthalmic interferometry, which essentially showed that measuring reflected light could be used to...

Outcomes at 100 weeks from the LEAVO study of intravitreal anti-VEGF therapies for macular oedema secondary to central retinal vein occlusion

23 May 2019 |
Royal College of Ophthalmologists Annual Congress 2019, Glasgow - First presented and discussed on Monday 20 May 2019, with a further presentation of results during Retina Subspecialty Day on Thursday 23 May 2019. Among patients with macular oedema secondary to...

Effective treatment for rare sight-threatening infection

1 November 2023 | Moorfields, UCL, SIFI S.p.A., Acanthamoeba, keratitis, corneal infection
A drug candidate, based on pioneering UCL and Moorfields Eye Hospital research and currently under development by SIFI S.p.A., has been found to be highly effective in treating a rare sight-threatening eye infection in a new international clinical trial.

District hospitals key to unlocking Global South surgical conundrum

20 December 2024 | research, LMICs, international, surgery
Patients attending first referral hospitals in low- and middle-income countries (LMICs) receive surgical care that is just as safe and effective as that provided by higher level referral centres, a new study reveals. Researchers found no significant difference in 30-day...

Toxic nutritional optic neuropathy (TON)

2 August 2022 | | EYE - General
Toxic optic neuropathy are a group of conditions manifested by reduction of visual functions secondary to damage to the anterior visual pathways from exposure to a toxin. The implicated toxin could be work-based, food or drink related, or iatrogenic medication....

The results of the last survey Feb22

1 February 2022 | | EYE - Cataract, EYE - Refractive, EYE - General
This edition’s survey took a slightly different tack and tried to look at the problems we face in litigation. Litigation is unpleasant. It is horrible being involved in it and the process of litigation can be extremely stressful. From the...

Cytomegalovirus retinitis post intravitreal triamcinolone in an immunocompetent patient with juvenile glaucoma

1 December 2014 | | EYE - Cataract, EYE - Cornea, EYE - General, EYE - Glaucoma, EYE - Imaging, EYE - Neuro-ophthalmology, EYE - Oculoplastic, EYE - Oncology, EYE - Orbit, EYE - Paediatrics, EYE - Pathology, EYE - Refractive, EYE - Strabismus, EYE - Vitreo-Retinal
Figure 1: Fundus photograph shows active CMV retinitis four weeks after IVTA in the right eye. Figure 2: Fundus photograph of the left eye with no CMV retinitis; atrophic disc as a result of juvenile glaucoma. Case report A 29-year-old...

World-first platform for transparent, fair and equitable use of AI in healthcare

25 November 2025 | artificial intelligence, diabetes, diagnostics, research
Revolutionary AI platform for detecting diabetic eye disease proven safe for NHS. Researchers have developed the world’s first real-world head-to-head testing platform to determine whether commercial artificial intelligence (AI) algorithms are fit for NHS use to detect disease in a...