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Transient thickening of the macular retinal nerve fibre layer in acute optic neuritis

Acute optic neuritis (ON) causes axonal degeneration, which can be quantified from the blood by neurofilament protein (Nf) levels. Within about three months, atrophy of the retinal nerve fibre layer (RNFL) follows. However, it remains challenging to explain why there...

Elevated risk of mood disorders after recurrent retinal detachment

This study was aimed to investigate the risk of mood disorders in patients who experienced retinal detachment (RD) by using the National Health Insurance Research Database in Taiwan. A total of 4129 participants diagnosed with RD and 16,516 non-RD individuals...

Association between neurodegeneration and macular perfusion in the progression of diabetic retinopathy

In this prospective three-year longitudinal study, the authors aimed to explore the relation between retinal neurodegenerative changes and vessel closure (VC) in individuals with non-proliferative diabetic retinopathy (NPDR). The participants included 74 individuals with type 2 diabetes, NPDR, and Early...

Optic disc pit maculopathy: an optical coherence tomography study

This was a single-centre, retrospective observational case series that aimed to analyse the change of optical coherence tomography (OCT) characteristics in the natural course of optic disc pit maculopathy (ODP-M) and their effects on visual acuity. Twenty-two eyes of 22...

The potential of artificial intelligence and digital health in global eye health

This article provides an overview of the current landscape of artificial intelligence (AI) and digital health in global eye health. Tan, et al. note that though significant progress has been made in global eye health over the last few decades,...

EDOF intraocular lens in eyes with preexisting retinal disease

Extended depth of focus (EDOF) intraocular lens (IOL) offers improved near and intermediate vision, aiming to reduce spectacle dependence in cataract patients. This study aims to evaluate the performance of EDOF lenses following cataract surgery in patients with retinal pathology....

AI-Based devices in national screening programmes: barriers and challenges

Diabetic retinopathy (DR) may have long-term complications and is recorded as a leading cause of blindness. National DR screening programmes have effectively reduced severe visual loss by timely detection and subsequent treatment of sight-threatening proliferative DR and diabetic macular oedema....

The art of giving generous grains

On the drive home, after a long day of eye screening patients in homeless shelters, I would pass through the boroughs, towns and villages of east London. Stopping at the soup kitchen, I would meet Christian with heavy cataracts, and...