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3422 results found

Histopathological changes in rabbit retinitis pigmentosa

The authors report the histopathological changes of retinal ganglion cells (RGCs), optic disc and optic nerve in rabbit with advanced retinitis pigmentosa (RP). RP was recreated in rabbits by using bacterial artificial chromosome transgenesis, with the purpose of increasing understanding...

Macular thickness after strabismus surgery

The aim of this study was to determine whether strabismus surgery is associated with changes in macular thickness as detected by OCT. The study included 60 eyes of 30 patients with mean age of 28.9±14.2 years undergoing unilateral surgery. Mean...

High myopia macular thickness

The purpose of this study was to compare macular thickness and volume in 15 highly myopic (>-6D) young children with 11 age-matched controls (-2 to +4D refractive errors) using Stratus third generation OCT. Mean spherical equivalent was -9.42 ±2.81D for...

The clinical spectrum of albinism

The authors sought to examine clinical correlates that may be related to foveal development in albinism with an aim to qualitatively describe the phenotype spectrum of albinism. Binocular best corrected visual acuity ranged from 20/20 to 20/80. Best corrected visual...

OCT angiography metrics in children

This prospective study aimed to quantify the vessel density of both the macular and optic nerve and foveal avascular zone (FAZ) values in 92 normal eyes of 92 children (42 boys, 50 girls) aged 13.4 ±2.65 years (seven to 18)....

Chorioretinal atrophy in punctate inner choroidopathy / multifocal choroiditis

This study reported the five-year outcomes of chorioretinal atrophy (CRA) progression in patients with punctate inner choroidopathy (PIC) or multifocal choroiditis (MFC) in 45 eyes of 36 patients. The mean age of the cohort of patients was 37 ±13.37 years...

A paradigm shift: re-defining success in retinal detachment repair

The authors describe in this review article that functional outcomes vary with surgical technique for retinal detachment repair. Traditional definitions of surgical success have been shifted due to advances in imaging techniques. Assessment of the integrity of retinal reattachment including...

Covid-19 ophthalmopathy

Ocular involvement is not uncommon in patients with Covid-19. However, the incidence of Covid-19 ophthalmopathy is unclear. The authors present a prospective case series including 2445 consecutive cases presenting at a neuro-ophthalmology clinic during the last resurgence of SARS-CoV-2 infection....

Understanding the pachychoroid disease spectrum

This article provides a comprehensive review of the pachychoroid disease spectrum, a group of chorioretinal disorders characterised by abnormal choroidal thickening and various pathological changes in the choroid, retinal pigment epithelium, and retina. It also highlights the controversies and knowledge...

Congenital and paediatric cataract: Advances in diagnosis and management

Congenital and paediatric cataracts are relatively rare, although prevalence varies significantly between countries, influenced by factors such as nutrition, immunisation policy and population genetics [1]. In the UK, around 3–4 of every 10,000 babies are born with cataracts. It’s a...

SOS (Simplified Ophthalmic Statistics) Part 2: How to summarise your data and why it’s a good idea to do so

Studies involve capturing data. Statistical techniques allow data to be used to answer important research questions. A case series may have data on a handful of subjects but we are now entering the Big Data arena where datasets can be...

Clinical Observation Days Pave Way for Next Generation of Optometrists

Optometry students at Glasgow Caledonian University have taken part in a series of clinical observation days at one of the UK’s leading eye surgery clinics, as part of a new programme giving student optometrists experience of modern day surgical practice.