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The bionic eye – behind the headlines

Multiple visual prosthetic projects and other vision regeneration initiatives being tested in preclinical and clinical development worldwide illustrate continuing progress and opportunities in addressing profound blindness from hereditary retinal diseases and other causes (Table 1). Three implantable bionic vision systems...

Refraction planning in cataract: avoid creating an unhappy patient

“It is much more important to know what sort of a patient has a disease than what sort of a disease a patient has.” William Osler The focus of this paper is the prevention of an unhappy patient following cataract...

Reflections on deployment to ICU

Being unexpectedly uprooted from ophthalmology to ICU during the coronavirus pandemic was certainly a challenge, not just clinically, but emotionally and personally. However, it is only through adversary that we learn to appreciate what we have, and there are definitely...

NHS leaders must support doctors to act on new GMC guidance to challenge concerning behaviour at work

Dr John Holden responds to the publication of the revised Good Medical Practice (GMP) guidance from the General Medical Council.

Treatment options for septic cavernous sinus thrombosis

Septic cavernous sinus thrombosis is a rare but serious complication of infection of the cavernous sinuses. Potential therapies include antibiotics, corticosteroids and anticoagulation, as well as surgical intervention for source control of the infection. The authors report that there is...

Three muscle surgery results for ET

There is limited information in the literature on the outcomes of three muscle surgery. The authors aimed to evaluate the medium term motor outcomes of three horizontal muscle surgery in 18 patients with large angle infantile esotropia of at least...

Effect of voriconazole of vision of healthy volunteers

Voriconazole is a broad spectrum, triazole antifungal agent used for systemic fungal infections. It has a favourable safety profile and is available in both intravenous and oral forms. The commonest adverse drug reactions with voriconazole are changes in visual perception,...

Chloral hydrate sedation

A systematic review of literature sourced from PubMed, EMBASE, ISI, Web of Science, Scopus, CENTRAL, Google Scholar and Trip database to 1 October 2015, about the safety and efficacy of chloral hydrate (CH) by meta-analysis of randomised controlled trials (RCTs)...

Modern trabeculectomy outcomes

This audit was conducted by the Trabeculectomy Outcomes Group Audit Study Group to report on the efficacy and safety of current trabeculectomy surgery in the UK. This is relevant in light of the fact that the trabeculectomy outcomes presented by...

The long-term effects of AREDS on AMD progression

The Age-Related Eye Disease Study (AREDS) was an 11-centre, double-masked, clinical trial that in 2001 found a high-dose of antioxidant vitamins plus zinc was effective in protecting against progression of age-related macular degeneration (AMD) in patients with moderate to high...

Beta blocker treatment for capillary haemangioma

This randomised controlled trial of 25 patients aimed to evaluate the safety and efficacy of combined oral and topical beta blockers for the treatment of superficial periocular infantile capillary haemangioma at the early proliferative stage. Group 1 (n=13) were given...

Combined versus traditional photocoagulation treatment for aggressive posterior retinopathy of prematurity (APROP)

The purpose was to report the outcomes of the combined treatment of sparing laser photocoagulation and intravitreal Bevacizumab (IVB) treatment versus conventional laser photocoagulation intervention in APROP. This was a study of 18 eyes of nine infants. One was excluded...