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Effects of idiopathic intracranial hypertension on the optic nerves
The authors review the latest evidence regarding how the optic nerves are affected by idiopathic intracranial hypertension (IIH), possible pathophysiology and methods of assessment. IIH is described as a clinical syndrome of raised intracranial pressure of unknown aetiology. A systematic...
Oral Ibuprofen reduces early bleb failure in high risk trabeculectomy
In this retrospective cohort study, 288 eyes of 273 patients (mean ±SD age: 68.56 ±10.47 y; 32.60% females) with primary glaucoma who underwent trabeculectomy / phacotrabeculectomy at the Singapore National Eye Centre between April 2020 and April 2021 with a...
Manual for Eye Examination and Diagnosis (Tenth Edition)
This is a single author published manual which aims to equip the novice reader with a short, yet comprehensive introduction to ocular examination and diagnosis. This book has a substantial history, having been first published 48 years ago, and is...Aspiration of anteriorly migrated dexamethasone implant using an 18G intravenous cannula
Intravitreal dexamethasone (Ozurdex 0.7mg) is a biodegradable, sustained-release implant used to manage diabetic macular oedema, macular oedema secondary to retinal vein occlusion, and non-infectious posterior uveitis due to its anti-inflammatory effects and VEGF suppression [1]. While effective, the implant may...A woman who has had two emergency eye operations ran her first Edinburgh Marathon on May 28th
Gail Burns, from Edinburgh, ran to fundraise for sight loss charity, RNIB Scotland, who supported her father in his diagnosis of age-related macular degeneration just two years ago.Optometrist found guilty of manslaughter
To start our new Optometry section, editor Janet Pooley takes a look at the tragic death of Vincent Barker and asks what lessons can be learned. In August, Optometrist Honey Rose was found guilty of the manslaughter of eight-year-old Vincent...
Chronic lymphocytic leukaemia (CLL) of the lacrimal sac
The authors present a case series of three patients with known CLL, two of which presented with mass and epiphora and one case with epiphora alone. All three patients had initially being diagnosed and were treated for chronic dacryocystitis. Histopathological...
Retinoblastoma chemotherapeutic drugs and their toxic effects on RPE cells
There is reported clinical evidence of retinal pigment epithelium (RPE) alterations after intra-arterial (IAC) and intravitreal chemotherapy (IViC) of retinoblastoma. The purpose of this study was to investigate the cellular toxic effects of melphalan, topotecan and carboplatin on the RPE...
Squamous metaplasia of conjunctival epithelial cells with soft contact lens wear versus non-lens wearers
Conjunctiva is composed of non-squamous epithelial cells interspersed with goblet cells, which is a secretory epithelium. Squamous metaplasia is a transformation to non-secretory epithelium, ‘keratinised’ and enlargement of the conjunctival non-goblet cells and relatively shrunken nuclei are seen on impression...
Are corneal guttata an additional risk factor in complicated cataract surgery needing a future corneal transplant?
This registry-based cohort study from Sweden utilised data from the Swedish National Cataract Registry and the Swedish Cornea Transplant Registry. Patients who underwent phacoemulsification with a posterior intraocular lens between 2010 and 2012 numbered 192,476. Of these cases, 288 underwent...
