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Acta Ophthalmologica cover image.

Retinoblastoma chemotherapeutic drugs and their toxic effects on RPE cells

1 October 2016 | | EYE - Vitreo-Retinal
There is reported clinical evidence of retinal pigment epithelium (RPE) alterations after intra-arterial (IAC) and intravitreal chemotherapy (IViC) of retinoblastoma. The purpose of this study was to investigate the cellular toxic effects of melphalan, topotecan and carboplatin on the RPE...

Squamous metaplasia of conjunctival epithelial cells with soft contact lens wear versus non-lens wearers

1 December 2014 | | EYE - Cornea, EYE - Pathology, EYE - Oncology, EYE - General
Conjunctiva is composed of non-squamous epithelial cells interspersed with goblet cells, which is a secretory epithelium. Squamous metaplasia is a transformation to non-secretory epithelium, ‘keratinised’ and enlargement of the conjunctival non-goblet cells and relatively shrunken nuclei are seen on impression...
JCRS journal cover image.

Are corneal guttata an additional risk factor in complicated cataract surgery needing a future corneal transplant?

3 June 2021 | | EYE - Cataract, EYE - Refractive
This registry-based cohort study from Sweden utilised data from the Swedish National Cataract Registry and the Swedish Cornea Transplant Registry. Patients who underwent phacoemulsification with a posterior intraocular lens between 2010 and 2012 numbered 192,476. Of these cases, 288 underwent...
Seminars in Ophthalmology journal cover image

Does lower eyelid entropion repair alter corneal topography?

1 February 2022 | | EYE - Cornea, EYE - General
The authors aimed to analyse the corneal morphology before and after advancement of posterior lower eyelid retractors (LERs) alone or in combination with a lateral tarsal strip (LTS) for lower eyelid involutional entropion. Retrospective analysis of 24 consecutive elderly patients...
Manual for Eye Examination and Diagnosis (Tenth Edition) front cover image.

Manual for Eye Examination and Diagnosis (Tenth Edition)

1 October 2021 | | EYE - General
This is a single author published manual which aims to equip the novice reader with a short, yet comprehensive introduction to ocular examination and diagnosis. This book has a substantial history, having been first published 48 years ago, and is...

The third #AspireOphth Competition is here!

17 May 2024 | | #AspireOphth, competition, free book, giveaway, FRCOphth, Part 1, Sohaib Rufai, RCOphth2024, EyeConUK, conference, event, meeting, congress, RCO24
The RCOphth 2024 Annual Congress / #EyeConUK is coming up and you know what that means, we're teaming up again with Sohiab R Rufai for another #AspireOphth Competition!

A woman who has had two emergency eye operations ran her first Edinburgh Marathon on May 28th

30 May 2023 | AMD, RNIB, charity, Fundraising
Gail Burns, from Edinburgh, ran to fundraise for sight loss charity, RNIB Scotland, who supported her father in his diagnosis of age-related macular degeneration just two years ago.

Optometrist found guilty of manslaughter

1 December 2016 | EYE - General
To start our new Optometry section, editor Janet Pooley takes a look at the tragic death of Vincent Barker and asks what lessons can be learned. In August, Optometrist Honey Rose was found guilty of the manslaughter of eight-year-old Vincent...

Specialty doctor interviews

1 February 2019 | | EYE - General
I started my training as an ophthalmologist in the Wild West of Carmarthenshire where I did my first laser procedure, first phacoemulsification and first slit-lamp examination. All of these firsts were done under the tutelage of very skilled staff grade...

Boosting key protein in eye cells could prevent age-related vision loss, international team finds

6 June 2024 | amd, protein, vision loss, age-related, macular, research, paper, IRAK-M
Increasing the levels of a key protein in the cells at the back of the eye could help protect against the leading cause of vision loss among older adults, finds a new discovery made by researchers from the UK, US, Germany and Australia.

Can 3D facial imaging improve patient management in disfiguring eye disease?

1 August 2015 | | EYE - Imaging, EYE - Oculoplastic
Fight for Sight is the leading UK charity funder of eye research. Since the 2013 Sight Loss and Vision Priority Setting Partnership we have encouraged our researchers to work on priorities jointly identified by people affected by sight loss and...

Trabeculectomy with erroneous Mitomycin-C concentration – a near miss

1 April 2020 | | EYE - Glaucoma, EYE - General
Trabeculectomy is the most commonly performed surgical procedure for glaucoma in the United Kingdom and worldwide. Modifications to the technique have been made since its introduction in 1963, perhaps the most significant being the adjunctive use of mitomycin-C (MMC), which...