You searched for "pathology"

1342 results found

Unexplained vision loss following exposure to combat

Non-organic vision loss (NOVL) is defined as a decrease in visual acuity or visual field without an identifiable organic cause. NOVL can be particularly challenging and time-consuming to diagnose, especially where the vision loss is superimposed on an element of...

Chronic lymphocytic leukaemia (CLL) of the lacrimal sac

The authors present a case series of three patients with known CLL, two of which presented with mass and epiphora and one case with epiphora alone. All three patients had initially being diagnosed and were treated for chronic dacryocystitis. Histopathological...

Prognostication for uveal melanoma

The authors highlight the importance of using all available data in the prognostication of uveal melanoma (UM). Over recent years a number of molecular tests have emerged to allow clinicians to predict metastatic potential of UM. However, concordance between techniques...

Atopic keratoconjunctivitis (AKC) and ocular surface squamous neoplasia (OSSN)

The authors present two cases of invasive OSSN in patients with severe AKC. Case 1 was a 73-year-old male with severe AKC and atopic eczema who developed a suspicious papillary-like limbal lesion in the left eye. He had an excisional...

Froben for anterior scleritis

Flurbiprofen (Froben) is one of the nonselective cyclooxygenase (COX) inhibitors blocking both COX-1 and COX-2 pathways. Agrawal et al. undertook a retrospective cohort study to determine the effectiveness of oral Froben in managing noninfectious, non-necrotising anterior scleritis. One hundred and...

Aqueous humour cytokine levels in PCV and nAMD

This study looks into the possible roles of various cytokines or growth factors in the pathogenesis of exudative age-related macular degeneration (AMD) by comparing aqueous levels of 14 cytokines between eyes with polypoidal choroidal vasculopathy (PCV) and those with neovascular...

Cataract surgery in patients with retinitis pigmentosa

Retinitis pigmentosa (RP) is the commonest inherited cause of retinal degeneration. Posterior subcapsular cataract (PSC) develops in 41% to 90% of these patients by age 40 years. In this retrospective study, the authors have evaluated surgical outcomes in patients with...

Quality of life concerns after uveal melanoma diagnosis

The authors sought to investigate factors associated with Quality Of Life (QOL) after initial diagnosis of uveal melanoma (UM) using prospectively collected data between September 2011-May 2016. They included 201 participants referred for radiotherapy after UM diagnosis by an ophthalmic...

Cutaneous malignant melanoma metastasis to pseudophakic lens

Metastases to the eye and orbit are rare and intraocular cutaneous malignant melanoma metastasis (ICMM) is exceedingly rare, representing around 5%. There have only been three previous cases of ICMM to the lens in the literature, all of which presented...

Retinoblastoma in older children

Retinoblastoma is the most common ophthalmic malignancy in childhood and over 90% are diagnosed before the age of five years. It is not often suspected in older children given its rarity and unusual clinical findings which complicates the diagnosis. The...

Steroid treatment for pseudophakic cystoid macular oedema

The authors present a retrospective comparison of 45 eyes of 41 patients treated with 2mg intravitreal triamcinolone (IVT group) and 50 eyes of 42 patients treated with 40mg sub-Tenons triamcinolone (STT group) for pseudophakic cystoid macular oedema (CMO). The visual...

Can retinal layer thickness predict the progression of disability in MS?

This is an observational retrospective cohort study presenting the data of 188 patient diagnoses with multiple sclerosis at two specialist centres. All included patients were adults below the age of 70 years, stable on their disease modifying treatment for at...