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Cornea journal cover image.

Central corneal and epithelial thickness measured by Fourier domain OCT

1 April 2016 | | EYE - Cornea, EYE - General
This study examined intraobserver and interobserver reproducibility of corneal thickness (CT) and epithelial thickness (ET) measurement of Fourier domain OCT (RTVue) in 23 healthy volunteers. RTVue is capable of producing 26,000 A scans per second with depth resolution of 5µm....
Current Eye Research journal cover image.

Cataract in patients with pseudoexfoliation syndrome

1 August 2018 | | EYE - Cataract, EYE - Refractive | Apoptosis, TUNEL, cataract, lens epithelial cell, pseudoexfoliation syndrome
The authors present a prospective comparative study in 43 patients with (group 1) or without (group 2) pseudoexfoliation (PXF) undergoing cataract surgery. Anterior capsule samples were obtained in all patients and analysed for signs of apoptosis by using special staining...
Current Eye Research journal cover image.

The effect of everolimus on retinal pigment epithelium and proliferative vitreo-retinopathy

1 August 2018 | | EYE - Vitreo-Retinal
The principal cells involved in proliferative vitreo-retinopathy (PVR) are retinal pigment epithelial cells (RPE). Everolimus is a drug used in renal cell carcinoma which targets and inhibits a key regulatory protein in cancer (mTOR). In this study, the authors investigated...
Ophthalmic Research journal cover image.

Complement Factor H and Factor H-Like protein are expressed in human RPE cells

1 April 2014 | | EYE - General
The role of inflammation in age-related macular degeneration (AMD) is well documented and the association of AMD with the inflammatory marker C-reactive protein (CRP) and members of the complement system underline the role of complements in AMD. Human complement factor...

Erythropoietin in healing corneal epithelial defects in rabbits

1 December 2013 | | EYE - Cornea, EYE - General
Corneal epithelial defects heal slowly in patients with diabetes, limbal stem cell deficiency and severe chemical burns. Erythropoietin is a glycoprotein hormone that promotes red blood cell proliferation and inhibits apoptosis of erythroid progenitors as well as nonhematopoietic cells. In...

Nurse-led Rapid Corneal Collagen Cross-linking / UKISOP Society Education Day

1 December 2013 |
Nurse-led Rapid Corneal Collagen Cross-linking By Dan Gore Over the last decade, clinical trial data has accumulated for new interventions in keratoconus that promise to arrest disease progression, significantly reduce transplantation rates and save many patients from long-term reliance on...

Surgical options for the treatment of hyperopia

1 August 2016 | | EYE - Cataract, EYE - Refractive
The modern refractive surgeon has a variety of options available to treat patients with hyperopia who wish to be independent of spectacles and contact lenses. Unlike in low myopia where presbyopic patients may have the ability to see well for...

My experience of the transition into a specialist orthoptist role

1 August 2018 | | EYE - General
Michelle Dent discusses the process of transitioning into a new role and the pros and cons along the way. An opportunity arose for a permanent, full time, band 7 specialist role in the medical retina (MR) team in the Newcastle...

A Multidisciplinary Approach to Neovascular Glaucoma in a Patient with Waldenström’s macroglobulinemia

1 December 2013 |
An 84-year-old Caucasian male attended eye casualty with a four month history of reduced vision, a dull ache and photophobia in both eyes. He had also reported dizziness, weakness and intermittent epistaxis in the nine months prior to presentation. There...

Amnion-assisted conjunctival epithelial redirection (ACER): Enhancing stem cell transplantation treatment of total limbal stem cell deficiency

1 April 2019 | | EYE - Cornea, EYE - General
An exploration of Professor Harminder Dua’s recent work using a technique called amnion-assisted conjunctival epithelial redirection (ACER) to aid the success of conjunctival-limbal grafting procedures. ACER provides a refined way to use amniotic membrane (amnion), such as Omnigen® (NuVision® Biotherapies,...

Ocular surface special: Ocular manifestations of Stevens-Johnson syndrome

11 June 2026 | | EYE - Cornea, EYE - Pathology
Stevens–Johnson syndrome (SJS) is an uncommon dermatological emergency on the same clinical spectrum as toxic epidermal necrolysis (TEN). SJS is characterised by an acute, immune-mediated attack on the skin and mucous membranes, producing a rapidly progressive erythematous eruption with blistering...

Quiz Aug/Sep 2025

4 August 2025 | | EYE - Cornea
History A 78-year-old female presented with bilateral, painless, progressive blurring of vision over five years, photophobia and increasing glare. Her past medical history included a known diagnosis of monoclonal gammopathy of undetermined significance (MGUS). On examination, vision in the left...