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Investigation of PAX7 positive satellite cells in extraocular muscle surgery
PAX7 is a transcription factor and is expressed in non-active and activated satellite cells. It is needed for muscle progenitor function, survival and expansion. This study investigates the effect of recession/resection surgery on PAX7-positive satellite cells in extraocular muscles of...Sight loss experts warn Edinburgh eye health being neglected
Sight Scotland and Sight Scotland Veterans launch petition calling for new eye hospital in the capital.Inherited retinal disorders now the leading cause of blindness
The recent paper in BMJ Open, from the UCL Institute of Ophthalmology, ‘A comparison of the causes of blindness certifications in England and Wales in working age adults (16-64 years), 1999-2000 with 2009-2010’ concludes that inherited retinal disorders (IRD) such...New Ophthalmic Nurse Triage Course launched
A new online Ophthalmic Nurse Triage Course has been developed by Stanley Keys, an experienced hospital optometrist based in Inverness and developer of Optometry Evolution (an educational website for eye-care professionals.)Moorfields: Oculoplastic nursing and allied professionals study day
This one day in-person course is designed to improve clinical practice and knowledge by highlighting new ways of working within this specialty.
Dilate or not in subconjunctival haemorrhage?
There is often surprisingly little evidence in common clinical conditions. Spontaneous non-traumatic subconjunctival haemorrhage (SCH) is frequently encountered in emergency and walk-in clinic visits. In some centres, a dilated fundus exam is performed to exclude retinal pathology. This retrospective study...
Three methods of suppression measurement
Test-retest reliability and interchangeability are evaluated for three filter bars available to measure density of suppression: Sbisa bar, Bagolini filter (BF) bar and neutral density filter (NDF) bar. The study involved 10 strabismic adults. Testing conditions were altered and effects...
PD-1 and retinal ganglion cell death
Death of retinal ganglion cells (RGC) in conditions like glaucoma leads to permanent visual loss. RGC death can be due to the initial stress such as raised intraocular pressure or secondary to mechanism such as oxidative stress. Programmed cell death-1...
Differential inhibition of EAU by CTLA4 and IL-6
Cytotoxic T lymphocyte antigen-4 (CTLA4) binds both CD80 and Cd86 and inhibits T lymphocyte activation via CD28. Il-6 is a pleiotropic cytokine that has been associated with many autoimmune conditions including uveitis. Blockade of these molecules by either CTLA4-Ig, a...
Patient-reported outcomes in oculoplastic surgery
This is an important if somewhat difficult to grasp article which tries to formally address the subject of patient-reported outcomes in oculofacial surgery. The authors have conducted an extensive review of the literature searching for instruments (questionnaires) which have been...
Topical doxycycline for corneal neovascularisation
Six eyes with corneal vascularisation were treated with 1% topical doxycycline, four times a day for three weeks. The patients were reviewed at various intervals over a period of one year. The eyes selected had neovascularisation secondary to a variety...
