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Oral proton pump inhibitors in macular degeneration patients
The authors report five patients with advanced wet macular degeneration and poor vision with onset or enhancement of visual hallucinations with the use of proton pump inhibitors for heartburn management. The hallucinations were reversible with discontinuation of medication. The authors...
Impact of medical vs. surgical treatment on quality of life in glaucoma patients
The author recruited 225 patients across two sites and divided them into three groups. Group 1 medical treatment only, Group 2 surgical treatment only, Group 3 mixed medical and surgical (patients still on drops after surgery). They then used a...
The long-term effects of AREDS on AMD progression
The Age-Related Eye Disease Study (AREDS) was an 11-centre, double-masked, clinical trial that in 2001 found a high-dose of antioxidant vitamins plus zinc was effective in protecting against progression of age-related macular degeneration (AMD) in patients with moderate to high...
Outcomes with small aperture IOLs
This study aimed to compare the clinical outcomes following the implantation of an extended depth of focus small-aperture intraocular lens (IOL) (IC-8; AcuFocus, Irvine, CA) for presbyopia correction when implanted monocularly or binocularly. Visual outcomes, defocus curve, patient satisfaction, and...
Review of extraocular muscle biopsies and utility of biopsy in extraocular muscle enlargement
This is a retrospective case series study from Melbourne, Australia, of 93 patients with extraocular muscle (EOM) enlargement who underwent an EOM biopsy between March 1992 and January 2017. Statistical analysis was performed to compare the data between patients with...
Low dose steroids with elevated IgG4 levels
This is a retrospective case series review of 28 biopsy-proven IgG4-related ophthalmic disease (ROD) patients treated between March 2010 – January 2017 from Seoul, Korea. The mean follow-up period was 27.3 months. Lacrimal glands were involved in all patients and...
Is serum ACE useful in diagnosing sarcoidosis in uveitis patients?
This retrospective clinical notes review assesses whether serum angiotensin converting enzyme (ACE) is useful in the diagnosis of sarcoidosis in patients presenting with uveitis. There were 1035 consecutive subjects presenting with uveitis as part of baseline investigations had a serum...
Knobby eye syndrome
This study used high resolution MRI to demonstrate and evaluate globe shape in axial high myopia and identify and characterise those with prominent equatorial staphylomata that deflect extraocular muscle paths and presumably alter motility patterns in strabismus. The study included...
A case report showing the natural history of papilloedema
The case report describes a 54-year-old woman who developed increased intracranial hypertension due to chronic dural venous sinus thrombosis in the absence of any significant comorbidity. In the years preceding diagnosis, the patient underwent routine diabetic retinopathy screening; however, gradual...
IgG4-related disease or Graves orbitopathy
This is retrospective review of patients who had been diagnosed with both IgG4-related ophthalmic disease (IgG4-ROD) and Graves orbitopathy over a four year period. Eight patients were identified. The diagnosis of IgG4-ROD was based on 10 or more IgG4+ plasma...
IINS function
This study explored the impact of idiopathic infantile nystagmus syndrome (IINS) on quality of life in adults measured using the VFQ25 questionnaire. Of 38 subjects, 35 completed the questionnaire. Mean age was 35.1±13.0 years; 15 were British Caucasian and 14...
