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Therapeutic options for advanced cutaneous basal (BCC) and squamous cell carcinomas (SCC)
This article discusses the use of topical and systemic therapy in the management of advanced periocular tumours. It focuses on those that have gained United States Food and Drug Administration approval; namely imiquimod, vismodegib, sonidegib, pembrolizumab and cemiplimab. Imiquimod is...
Aetiology of painful ophthalmoplegia
Painful ophthalmoplegia is a clinical syndrome presenting with periorbital / hemi-cranial pain and ipsilateral ocular motor nerve palsies and can occur with numerous different diseases. In this study, the authors aimed to determine the final definite aetiology among patients with...Photophobia: an unusual symptom of a pituitary macroadenoma
Introduction Photophobia, defined as ‘an abnormal intolerance to light’, is commonly associated with a range of both ocular and neurological pathologies such as dry eye, blepharospasm, corneal pathologies, cataracts, uveitis, retinal dystrophies, optic neuritis, migraine, meningitis, and traumatic brain injury...What's trending Apr/May 2025
A round-up of the eye-related hot topics that have been trending on social media over the last few weeks. #ContactLens #Trapped I started wearing contact lenses in my teenage years and was always worried about them slipping behind my eyes....Take this waltz
My last weekend on-call was the busiest I can remember for a very long time. We were just completely swamped with patients. The weather was not too good that Saturday and it felt like every second inhabitant of our ocean...Oculoplastics: an evolving specialty
Consultant Ophthalmic and Oculoplastic Surgeon Raman Malhotra provides an insight into this increasingly popular subspecialty of ophthalmology. Oculoplastic surgery refers to plastic, reconstructive and aesthetic surgery of the eyelids, the surrounding facial areas, orbits and lacrimal system. Its scope has...A nightmare on Doctor Street: Three
“Everyone at this party isn’t as young, fit and single as they’re making out. Yep, let’s face it, we’re all falling apart piece by piece. Doesn’t matter if you’re single or in a couple: You. Are. Going. To. Die” In...
IgG4 related orbital disease
This retrospective study was done to determine the prevalence of IgG4 related orbital disease (IgG4ROD) in patients who previously had biopsies for suspected idiopathic orbital inflammatory disease (IOID) and / or orbital lymphoproliferative disease (OLD). The charts and slides of...Identifying life-threatening uveal melanoma: A directed application of general-purpose AI
Uveal melanoma (UM) is a rare but aggressive eye cancer, affecting approximately six people per million annually [1]. Uveal melanoma arises in three locations: the choroid, ciliary body, and iris. As the most common primary intraocular malignancy in adults, UM...6.6.2020 – a celebration of international partnerships
The date 6.6.2020 was selected as a significant milestone for celebrating the achievements of the VISION LINKS Programme as part of the global ‘VISION 2020: The Right to Sight’ initiative [1]. This virtual full-day seminar included LINK partners in the...What’s Eating Gilbert Pete
“Please phone Mr C Lyon ASAP on 0131 334 9171” This was a message from my secretary waiting for me on my computer one morning shortly after I was appointed a consultant. The name did not ring any bells but...
