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2572 results found

Ranibizumab safety in pregnancy

Vascular endothelial growth factor (VEGF) plays a pivotal role during pregnancy, and systemic anti-VEGF administration during this period should thus be avoided. VEGF is expressed in multiple embryonic and foetal tissues during development, with the highest levels found in the...

Portable corneal topography – exploration of a prototype

Ophthalmic imaging devices, such as corneal topographers, are not widespread in the developing world. A small device that connects to a smartphone might be a solution to improve developing nation access to corneal imaging. I recently had the opportunity to...

Genetic profiling for personalised healthcare solutions in AMD – an update

Age-related macular degeneration (AMD) is a multifactorial condition influenced by genetics and lifestyle factors (Table 1). This article outlines several recent advances in AMD genetics, as well as evolving therapeutic concepts and established practical measures for the treatment and /...

The vitreoretinal priesthood

When I first started doing cataract lists, the consultant at the time, a Mr Brown from Carmarthen, used to say that phacoemulsification was more akin to flying a jet fighter for short dangerous bombing runs than a boring long haul...

Effective management of dry eye and ocular surface disease

Experts recommend a consistent approach to diagnosis, therapeutic targeting by disease subtype and escalation of therapy when tear substitutes are not sufficient. Experts call for a consistent, unified approach to diagnosis of dry eye disease (DED), with a new simple...

Has ‘reduce, reuse and recycle’ gone too far?

The past few decades of surgery since the ‘mad cow disease’ have been dominated by a push to switch to disposable instruments. The reason is to prevent cross-contamination and reduce the risk of surgical site infections – especially so with...

Review of non-arteritic anterior ischaemic optic neuropathy

This article reviews the risk factors, clinical presentation and therapies that have been investigated for non-arteritic anterior ischaemic optic neuropathy (NAAION). Additionally, it provides an update from recent rodent and primate models, offering a new insight into the pathophysiology of...

Post-stroke visual impairment: how big is the problem, how do we identify it, what we can do about it, and why does it matter?

In the UK, 100,000 new strokes occur each year, with 1.3 million stroke survivors [1]. This article will focus on post-stroke visual impairment, discussing topics of how common it is, how it can be detected, possible management options and how...

Global health milestone as Pakistan becomes 19th country to eliminate blinding trachoma

Sightsavers commends Pakistan following the World Health Organization (WHO) announcement that it has become the nineteenth country to eliminate blinding trachoma as a public health problem. This phenomenal achievement means around 3.7 million people [1] in Pakistan are no longer...

What’s next in retinal imaging? Faster, deeper and full-on

Fast-evolving technological leaps are opening the way toward clinically useful ocular coherence angiography, generating 3-dimensional microvasculature maps without intravenous dye injection, as well as whole-eye imaging, handheld patient-operated optical coherence tomography (OCT) devices and, for challenging vitreoretinal procedures, integrated intraoperative...

Advances in cataract surgery

This article covers recent clinical findings in mydriasis and anaesthesia for cataract surgery, shared by Sathish Srinivasan and Keith Davey at a surgical meeting in Manchester. Towards dropless cataract surgery Day case cataract surgery is the standard of care in...

Registration is now live for 100% Optical 2025

It's time to ‘focus on the future’ with 100% Optical as they announce registration going live, a new look and website, confirmed sponsors and additional features for the 2025 exhibition. 100% Optical, the UK’s largest optical exhibition, is set to...