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Retinoblastoma chemotherapeutic drugs and their toxic effects on RPE cells
There is reported clinical evidence of retinal pigment epithelium (RPE) alterations after intra-arterial (IAC) and intravitreal chemotherapy (IViC) of retinoblastoma. The purpose of this study was to investigate the cellular toxic effects of melphalan, topotecan and carboplatin on the RPE...
Coeliac disease and anterior scleritis
The authors present an interesting case report of recurrent anterior scleritis. Circulating IgA and IgG auto-antibodies directed against tissue transglutaminase, endomisium and gliadin are frequently elevated in patients with coeliac disease. The classic symptoms remain chronic diarrhoea, malabsorption syndromes and...Video consultations after COVID-19
In the context of the COVID-19 pandemic, video consultations (VC) in eye care have been adopted in some regions and hospitals as a way of replacing some face to face ophthalmic consultations. I would like to use this column to...
A case presentation of morning glory disc anomaly and peripapillary staphyloma
The purpose of this paper is to present a case of an 18-month-old girl initially presenting with strabismus. Fixation of the affected eye was intermittent with a relative afferent pupillary defect. A fundus photography of the affected left eye showed...Bionic eyes: deciphering the neural circuitry of vision restoration
As the boundaries between technology and biology blur, retinal prosthetics, often dubbed ‘bionic eyes’, present a ground-breaking paradigm shift in addressing blindness. This article delves into the captivating scientific intricacies of these neural interfaces, exploring their mechanisms of action, current...
Ophthalmic DOPS and OSATS: The Handbook for Work-Based Assessments
The first thing to say is: “I wish I’d had this book when I was an ST1!” The number of work-based assessments (WBA) required during ophthalmic specialist training (OST) is a daunting prospect to trainee ophthalmologists, particularly ST1s with no...
Management of traumatic corneal perforations with anterior lamellar techniques: The mini-DSAEK
The authors present the first case report in which a mini (reduced diameter) Descemet’s stripping automated endothelial keratoplasty (mini-DSAEK) has been used to manage a traumatic corneal perforation. A 69-year-old male presented with 6/36 best spectacle-corrected visual acuity (BSCVA) and...What's trending Feb/Mar 2024
A round-up of the eye-related hot topics that have been trending on social media over the last few weeks. #ScleralTattoo #BlackEye Scleral tattoos aren’t necessarily a new phenomenon. A quick google search will identify cases being in the news from...Resurfacing the ocular surface
The ocular surface (OS) is an anatomical and functional unit made of the tear film, the conjunctival, limbal and corneal epithelium, the lacrimal, mucous and meibomian glands and the lids and blink reflex. The tear film is composed of a...
