You searched for "VEGF"

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Ophthalmology Review: A case-study approach (Second edition)

Ophthalmology review is a ‘case-driven’ textbook which is aimed at medical students or trainees. It’s quite an inviting textbook – I picked it up and flicked through and felt like this is something I would actually like to read. It...

NICE drugs: an update on what’s good to go

Treatment options recommended by the National Institute for Health and Care Excellence (NICE) must be readily available for use in the NHS of England and Wales. This article provides an overview of recent guidance from NICE and summary advice issued...

Does intravitreal bevacizumab help in diabetic retinopathy related vitreous haemorrhage?

This retrospective, interventional case series, aimed to assess the effectiveness of intravitreal bevacizumab (IVB) in vitreous haemorrhage secondary to proliferative diabetic retinopathy. The primary outcome was the rate of vitrectomy (PPV) after IVB, with secondary outcomes the number of IVB...

RPE tears after intravitreal Lucentis

The current hypothesis regarding retinal pigment epithelium (RPE) tears is the contraction and fibrosis in choroidal neovascularisation (CNV) tissue after anti-VEGF therapy can induce rips in the overlying RPE. This South Korean study aimed to identify the association between RPE...

The disease burden of AMD

In this multi-centre, prospective, observational, time and motion study the authors assessed the time burden of managing wet AMD for doctors, staff, patients and caregivers in the USA. The study spanned the period from March 2011 to August 2012, and...

Microvasculature changes of mCNV after ranibizumab treatment using OCTA

In this study the authors aim to evaluate the vascular changes of myopic choroidal neovascularisation (mCNV) after ranibizumab treatment using optical coherence tomography-angiography (OCTA). The 3×3 OCTA en face images were analysed for the absence / presence of mCNV, CNV...

The natural history of treatment naïve choroidal neovascularisation (CNV) in geographic atrophy

The aim of this retrospective study is to assess the characteristics and natural history of quiescent CNV in geographic atrophy (GA) utilising multi-modal imaging. Case notes were reviewed of patients diagnosed with geographic atrophy between January 2010 and December 2016...

The International AMD Genomics Consortium study: another success in understanding the complex genetics of AMD

Age-related macular degeneration (AMD) is a neurodegenerative complex disease of the eye and a major cause of blindness and visual impairment among the elderly worldwide. The early stages of the disease are characterised by asymptomatic pigmentary abnormalities and accumulation of...

How to consent patients

I attended a morning seminar at the recent College Congress in Liverpool about how to properly and legally consent a patient for a procedure. There has been a lot of interest in this of late following the Montgomery ruling, in...

The results of the last survey Dec21

Consent is a hot topic at the moment and the publication of the GMC Guidance on Consent [1] has rightfully refocussed our attention on it. Consent practices vary wildly and have been the subject of many of these surveys. Once...

Radiation retinopathy

The authors review the current treatment options for this condition. Radiation retinopathy (RR) occurs as a complication after exposure to any type of radiation (external beam, plaque brachytherapy and stereotactic radiosurgery) in the orbital or adnexal region. These include nasopharyngeal...

A life outside ophthalmology

Lloyd Paul Aiello. It was an absolute privilege to speak to Lloyd Paul Aiello, Professor of Ophthalmology, Harvard Medical School, and Vice President of Ophthalmology and Director, Beetham Eye Institute, Joslin Diabetes Center, USA. Prof Aiello is a third-generation ophthalmologist,...