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Risk factors for NTG in a young Korean population

Previously known ocular and systemic risk factors for normal tension glaucoma (NTG) include myopia, peripapillary atrophy, disc haemorrhage, migraine, obstructive sleep apnoea, thyroid disease and cerebral infarction. However, most NTG risk factor studies have examined patients aged 40 years and...

Brn3b neuroprotective effect in rat glaucoma model

An adeno-associated virus-directed overexpression of the Brn3b protein in hypothesised to confer neuroprotective effects in this paper. This is ultimately tested in a well-accepted rat glaucoma model (Morrison’s model: saline injection into episcleral veins of rat eyes with a force...

Rare case reports of benign optic glioma in adults with clinically aggressive nature

Primary optic nerve gliomas are most commonly benign and occurring in childhood. Malignant optic gliomas occur in adulthood and follow an aggressive course usually leading to blindness and death within months. This paper describes the clinical and histopathological features of...

Adolescent optic disc haemorrhages

The authors conducted this study to describe the clinical characteristics of multi-layered optic disc haemorrhages in adolescents. This was a retrospective review of 16 eyes (11 right and five left) of 16 patients with a mean age of 15 ±2.6...

Nasolacrimal duct screening to minimise post cataract endophthalmitis

This case control study compared the nasolacrimal duct (NLD) patency in a random sample of phacoemulsification cataract surgery patients (control group) versus a consecutive series of patients who developed endophthalmitis post cataract surgery (case group). NLD syringing was performed in...

Precision and accuracy of TearLab osmometer

Measuring tear osmolarity has been identified as a potential method for objectively diagnosing dry eye. TearLab osmolarity system is an in situ osmometer which may be a promising candidate for clinical use as it is portable and only requires a...

Functional visual field loss using automated static perimetry

Functional visual field loss is traditionally assessed by kinetic perimetry, typically producing spiralling isopters. This study looked at the spatial distributions of functional field deficits using automated static perimetry. A retrospective review of automated perimetry records was conducted using a...

Ocular blood flow changes in Behcet disease

This study evaluates ocular blood flow changes in both ocular Behcets disease (BD) and non-ocular BD (with or without thrombotic disease) and compares these findings with a healthy control group. A total of 90 eyes with BD were evaluated with...

Gender and ethnicity related differences in optic nerve head

The authors investigated the effect of ethnicity and gender on optic nerve head morphology comparing Indian and Caucasian males and females. The optic nerve head was investigated using spectral-domain optic coherence tomography (SD-OCT). Results showed that disc and rim areas...

Long-term outcomes for hereditary retinoblastoma

Earlier diagnosis and more rigorous treatment regimens have contributed to better outcomes for patients with retinoblastoma. This study looked at 24 patients with hereditary bilateral retinoblastoma treated with systemic chemotherapy during a ten year period (2001-2011). The medical notes were...

Diagnostic procedures in vitreoretinal lymphoma.

This paper presented a retrospective review of medical records of HIV negative immunocompetent patients diagnosed with vitreoretinal lymphoma between 1994 and 2012. The aim of the paper was to evaluate the type and number of diagnostic interventions required to confirm...

Vital dyes in ophthalmology

This comprehensive review gives an excellent summary of the uses and properties of the different dyes available to aid better visualisation and diagnoses in ophthalmology. The authors clearly display the pharmacological properties, molecular details, osmolarity and indications in clinical ophthalmology...