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The treachery of images – making sense of OCT imaging

1 June 2016 | | EYE - Vitreo-Retinal, EYE - Imaging
In 1929 Belgian surrealist Rene Magritte produced his painting La Trahison des Images. It depicted an old fashioned pipe for smoking tobacco and underneath were the words “ceci n’est pas une pipe”, this is not a pipe. You may wonder...

Eye scans detect signs of Parkinson’s disease up to seven years before diagnosis

22 August 2023 | moorfields, Parkinson's disease, Siegfried Wagner, Pearse Keane, UCL Institute of Ophthalmology, early detection
A team led by Siegfried Wagner and Pearse Keane of Moorfields Eye Hospital and UCL Institute of Ophthalmology (and spanning UCL institutions) has identified markers that indicate the presence of Parkinson’s disease in patients on average seven years before clinical presentation.

Survey: Dacryocystorhinostomy International Practice

2 October 2025 | Dacryocystorhinostomy, survey, research, standards, clinical practice
Dacryocystorhinostomy (DCR) is widely recognised as the gold-standard surgical intervention for managing nasolacrimal duct obstruction, particularly when medical therapy fails to restore adequate lacrimal drainage. Both external and endonasal (endoscopic) DCR approaches have evolved considerably over recent decades, with technological...

Comparison of SS-OCT and SD-OCT in polypoidal choroidal vasculopathy

1 April 2016 | | EYE - Vitreo-Retinal
Swept source OCT (SS-OCT) is known to have a longer wavelength than spectral domain OCT (SD-OCT), allowing deeper penetration into retinal and choroidal layers. The aim of this study was to investigate whether SS-OCT is superior to SD-OCT in imaging...
Ophthalmologica journal cover image.

Progression of macular atrophy on long-term anti-VEGF therapy for AMD

3 October 2022 | | EYE - Vitreo-Retinal | Anti-VEGF therapy, Long term, Macular atrophy, neovascular age-related macular degeneration
This retrospective study evaluated the progression of macular atrophy in 53 eyes of 53 patients receiving AntiVEGF Therapy for age-related macular degeneration (nAMD), for at least six years. None of the patients had any macular atrophy (MA) at presentation. MA...
Ophthalmologica journal cover image.

OCT prognostic factors in AMD patients with peripapillary choroidal neovascularisation

3 August 2023 | | EYE - Vitreo-Retinal
In this retrospective study the authors aimed to investigate the correlation between optical coherence tomography (OCT) findings and visual acuity outcomes after treatment with intravitreal bevacizumab (IVB) injections for age-related macular degeneration (AMD) patients with peripapillary choroidal neovascularisation (PPCNV). Data...

Upper eyelid ulceration as a presenting sign of frontal sinus mucocele

3 October 2022 | | EYE - General
Introduction A sinus mucocele is an epithelium-lined sac filled with mucus and desquamated epithelium. It forms secondary to inflammatory processes that occur in a sinus with an obstructed ostium. Predisposing conditions include previous trauma, surgery, tumours, anatomical abnormalities, and chronic...

NHS England launches tech trials to boost health and care connectivity

22 August 2023
NHS organisations are being invited to take part in wireless trials to explore how cutting-edge technologies can help improve patient care.

insitro and UK’s INSIGHT at Moorfields Eye Hospital announce collaboration to expand research efforts in neurodegeneration and related conditions

19 March 2025 | oculomics, artificial intelligence, AI, imaging, NHS
The world’s largest bioresource of eye images offers window into human health and serves as basis of a new AI foundation model to boost drug discovery. insitro, a machine learning-enabled drug discovery and development company, and the INSIGHT Health Data...

FMLM Conference 2024

26 March 2024
by Somain Verma, Ophthalmology Registrar (ST2), Northampton General Hospital. Clinical leadership is more important than ever. With an ever-increasingly burdened health system, we must assure that appropriate resources and systems are in place to maintain an effective and efficient health...

A trainee’s guide on how to prepare for the digital age of ophthalmology

6 April 2021 | | EYE - General
As the pandemic rolls on, the past year has left many ophthalmic departments in disarray with ever-lengthening patient waiting-lists and increasing challenges in service delivery. Areas such as virtual clinics, telephone / video consultations have had to mature rapidly to...

The role of inflammation in the pathophysiology of DMO

1 February 2016 | | EYE - Vitreo-Retinal
Diabetic macular oedema (DMO) is a major cause of visual loss in diabetes, with a complex multifactorial pathogenesis. In the UK alone it is estimated that there are nearly 2.5 million diabetic patients aged over 12 years. Approximately 65,000 of...