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Trabeculectomy for normal tension glaucoma
This is a retrospective consecutive, non-comparative case series of 131 eyes of 98 patients undergoing trabeculectomy between 2007 and 2013 in a normal tension glaucoma (NTG) clinic. Assessment of the clinical outcomes include intraocular pressures (IOP) reduction, bleb formation, final...
OCT angiography and retinal vein occlusions
In this retrospective, observational case series, the authors set out to evaluate the morphology of the superficial and deep capillary plexa of eyes that suffered a retinal vein occlusion (RVO) on OCT angiography (OCTA) and compare the findings with fluorescein...
Silicone band loop myopexy in the treatment of myopic strabismus fixus
This is a retrospective case series of chart review of patients who had silicone band loop myopexy between January 2008 to December 2012 for myopic strabismus fixus (MSF) at a tertiary eye centre in India. A minimum period of two...
Hyper reflective foci (HRF) on OCT in diabetic retinopathy
This study investigated the presence of hyper reflective foci (HRF) in asymptomatic patients affected by type 1 or type 2 diabetes, separately, without clinically significant diabetic macular oedema and visual impairment. In total 71 eyes with non-proliferative diabetic retinopathy were...
Visual performance of new multifocal IOL
Multifocal IOLs (MIOLs) keep evolving to try and get the best outcome in terms of vision and reduction of side-effects. This prospective interventional study was carried out on 34 eyes of 17 patients (11 women (65%) and six men (35%))...
Comparison of two interferon gamma release assays (IGRA) for tuberculous uveitis
In this prospective cohort study the authors compared QuantiFERON-TB Gold In-Tube and T-SPOT.TB to evaluate their diagnostic accuracy. They enrolled 120 consecutive new uveitis presentations over a two year period in a tertiary centre. The majority were Chinese (61.3%), followed...
Secondary iris-claw anterior chamber lens implantation in patients with aphakia without capsular support
This retrospective, non-randomised, non-comparative, interventional study including 128 eyes of 124 patients that presented with aphakia with no capsular support. All patients consecutively underwent Artisan iris-claw intraocular lense (IOL) implantation between 1997 and 2010. The inclusion criteria were: aphakic without...
Ginko bilboa extract affects hypoxic retinal pigment epithelial cells
Wet age-related macular degeneration (AMD) is characterised by choroidal neovascular membrane (CNVM) formation. It is thought that localised hypoxia within the retina results in overexpression of growth factors such as vascular endothelial growth factor (VEGF), which induces CNVM formation. VEGF...
A comparative evaluation of a new diffractive trifocal and EDOF IOLs
This study aimed to compare the outcomes of two diffractive trifocal intraocular lenses and one extended depth of focus (EDOF) intraocular lens (IOLs). This was a six month, single centred, prospective, randomised, comparative study in which patients who underwent routine...
Ranibizumab safety in pregnancy
Vascular endothelial growth factor (VEGF) plays a pivotal role during pregnancy, and systemic anti-VEGF administration during this period should thus be avoided. VEGF is expressed in multiple embryonic and foetal tissues during development, with the highest levels found in the...
Practice patterns of uveal melanoma management with Iodine-125 brachytherapy
With the 2006 Collaborative Ocular Melanoma Study Group (COMS) study demonstrating no difference in survival outcomes for participants randomised to either iodine-125 brachytherapy or enucleation, the majority of primary uveal melanomas in the United States are now treated with brachytherapy....
