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Lacrimal drainage system malignancies
This retrospective case series looks at the rare cases of lacrimal drainage system malignancies. The authors have identified 14 patients in 24 years, at a tertiary referral centre in the Indian subcontinent. Many previous publications have found squamous cell carcinoma...
Yolk sac tumours of the orbit and sinonasal tract
This paper outlines two case reports of patients with yolk sac tumours (YSTs) and carries out a review of the literature on this rare malignancy. YSTs are a type of germ cell tumour and primarily occur in the gonads. Ten...
Retrobulbar amphotericin B for rhino-orbital-cerebral mucormycosis
Rhino-orbital-cerebral mucormycosis (ROCM) is a rare and often fatal infection usually occurring in immunocompromised patients from diseases such as diabetes, haematological malignancy and solid organ transplantation. Current standards of care include systemic antifungal therapy and debridement, including exenteration. This study...
Understanding the extracellular matrix in uveal melanoma
This review examines how the extracellular matrix (ECM) is remodelled throughout uveal melanoma development, from the eye to the liver. Uveal melanoma, the most common primary intraocular malignancy in adults, carries a poor prognosis due to its propensity for hepatic...
Retinotopic fMRI reveals visual dysfunction and functional reorganisation in the visual cortex of glaucoma patients
This study investigated the retinotopic functional representation in the visual cortex of mild to moderate primary open-angle glaucoma (POAG) participants and age-matched normal volunteers, using wide-view visual presentation, high-resolution retinotopic stimuli, and high-resolution blood oxygenation level dependent (BOLD) functional magnetic...
Morning glory syndrome associated with PHPV
This is a retrospective review of the medical records of 85 eyes / 74 patients diagnosed as morning glory syndrome (MGS) in the clinic between November 2009 and November 2012. Twenty two eyes of 19 patients diagnosed as having MGS...
Rare presentation of giant cell arteritis in Chinese subjects
Only a few case reports of biopsy-proven GCA (BpGCA)-associated vision loss in Chinese subjects have been published. This paper presents three elderly Chinese subjects with BpGCA who presented with vision loss. A search of the literature was also conducted to...
Septo-optic dysplasia – a case note review
Septo-optic dysplasia (SOD) is a congenital disorder belonging to the midline brain malformation group. The condition manifests as a classical triad, including optic nerve hypoplasia (ONH), agenesis of midline structures (absent septum pel-lucidum and agenesis of the corpus callosum), and...
Clinical and anatomical differences for heavy eye syndrome, highly myopic sagging eye syndrome, and sagging eye syndrome
The authors explored the mechanisms underlying the development of heavy eye syndrome (HES), highly myopic sagging eye syndrome (SES)-like, and SES with the aim to differentiate the three conditions clinically and anatomically to aid treatment decision-making. This was a retrospective...
How common is empty sella in neuro-ophthalmology patients not suspected of raised intracranial pressure
The study aimed to assess how common the presence of empty / partially empty sella is amongst neuro-ophthalmology patients undergoing magnetic resonance imaging (MRI) excluding for papilledema and raised intracranial pressure (ICP). The study retrospectively reviewed case records of consecutive...
