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Methotrexate and mycophenolate mofetil for non-infectious uveitis
This is the first reported randomised clinical trial comparing methotrexate versus mycophenolate mofetil (MMF) for the treatment of non-infectious intermediate uveitis, posterior uveitis or panuveitis. To be eligible for recruitment, patients had to be on ≥15mg oral prednisone and demonstrated...
Management of restrictive diplopia after ptergium surgery
This single centre retrospective case series included 15 patients with restrictive diplopia after ptergium excision. The mean time from surgery to diplopia was six months and all patients had a moderate limitation of abduction in the operated eye causing an...
Review of bupivacaine use in treatment of strabismus
This review aimed to assess the applications of bupivacaine (B) in the non-surgical treatment of strabismus in human and animal studies. Animal studies show that singly-innervated fibres with low concentrations of mitochondria and developed sarcoplasmic reticulum are more affected by...
5-FU in cicatricial conjunctivitis
This is a retrospective review of 56 patients with cicatricial conjunctivitis, including 25 eyes that received sub-conjunctival injections of 25-50mg of 5-fluorouracil (5-FU) as part of their treatment. Thirty-seven patients had ocular cicatricial pemphigoid (OCP) and 19 had Stevens-Johnson syndrome...What's trending Dec/Jan 2021
A round-up of the eye-related hot topics that have been trending on social media over the last few weeks. #threeblindmice US company Nanoscope Therapeutics has developed a new treatment which is hoped will restore vision in those affected by retinal...
Ocular hypertension following intravitreal steroid injections: a comparative study between triamcinolone-acetonide and dexamethasone-implant
This was a retrospective observational study of steroid response following 1549 intravitreal steroid (TA and Dex) injections. One thousand and seventy-five eyes of 897 patients were reviewed. Glaucoma patients, glaucoma suspects, uveitis, trauma, and cases with less than one month...
Bupivicaine injection for Bell’s palsy
This study assesses the use of intramuscular bupivicaine to treat lid retraction and lagophthalmos in facial palsy. It is a prospective non-comparative interventional series of 10 patients with Bell’s palsy (House-Brackman grade IV or V) who each received three serial...Internuclear ophthalmoplegia: a case study
A 44-year-old patient presents with binocular, mostly horizontal diplopia when fixating on moving objects. This has been ongoing for approximately five years. He is known to have multiple sclerosis and had an episode of optic neuritis six years prior in...
Anatomical measurements for degree orientation and muscle insertions for rectus muscles
This study reports the relative degree orientation of the superior, lateral and inferior rectus muscles with respect to the medial rectus, and the distances between the rectus muscle insertions. The study involved 30 cadavers (60 eyes), all White, 50% female...
Lucentis for pseudophakic CMO
Pseudophakic cystoid macular oedema (CMO) develops angiographically in up to 20-30% after uneventful phacoemulsification. This study aimed to evaluate the potential efficacy and safety of intravitreal ranibizumab in patients with pseudophakic CMO after cataract surgery. Seven eyes were included in...
A case report of cavernous sinus syndrome following dental procedure
This case report describes a patient presenting with painful diplopia as a consequence of root canal dental treatment. Following root canal treatment a non-resolving tooth pain led to a decision to extract the tooth, leading to onset of severe periorbital...
