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Inherited retinal disorders now the leading cause of blindness

The recent paper in BMJ Open, from the UCL Institute of Ophthalmology, ‘A comparison of the causes of blindness certifications in England and Wales in working age adults (16-64 years), 1999-2000 with 2009-2010’ concludes that inherited retinal disorders (IRD) such...

What’s trending Feb/Mar 2026

A round-up of the eye-related hot topics that have been trending on social media over the last few weeks. #Darts #AlyPaly It always looks like an electric atmosphere at Alexandra Palace for the World Darts Championship, and the 2025/2026 competition...

A helping hand from Altomed

Your training journey is important and Altomed is here to help you build skills with confidence. That’s why, for a short time only, we’re offering a Buy 2, Get 1 Free promotion on 4 SimulEYE models (see website for full...

Exploiting nature’s randomised trials of eye disease

Confounding and reverse causation in observational ophthalmic epidemiology Traditional observational studies are inherently limited in establishing a causal effect of an exposure on an outcome of interest. One fundamental limitation is confounding, whereby causation is incorrectly attributed to a third...

Preview: Oxford Ophthalmological Congress

Between 1–3 July, we will be heading down to England for the 107th Oxford Ophthalmological Congress.

A life less miserable

Secret reveal… I love musicals! Ignoring regular derision from high-brow critics, musical theatre continues to maintain a strong presence in the hearts and minds of the people. Broadway and the West End thrive with new shows and classic productions entertaining...

MicroRNA inhibits corneal neovascularisation

MicroRNAs (miR) are small non-coding RNA that target mRNA for destruction. MiR target about 30% of the protein coding genes and fine tune their expression. MiR have been shown to be involved in several cellular processes including cell cycle, tissue...

Molecular genetics of achromatopsia

Achromatopsia is a rare autosomal recessive disorder of the cone photoreceptors. Typical characteristics of affected patients include the inability to distinguish colours, impaired visual acuity, photophobia and nystagmus. The condition is said to be more frequent in the Pingelapese population...

Comprehensive review of inherited retinal diseases

The authors offer an up-to-date review of inherited retinal diseases (IRDs). In each section the authors discuss the molecular basis of disease, genotype and clinical manifestation. They also discuss the investigation findings and current evidence in the treatment of the...

High score

Louie: “Allow me to present Pac-Man. Now, who is going to be the lucky pup who gets to play the first game? Iggy! You’re a somewhat compulsive personality. Step forward. Now… you see there’s the maze.” Iggy: “Uh-huh” Louie: “All...

What's trending Feb/Mar 2021

A round-up of the eye-related hot topics that have been trending on social media over the last few weeks. Happy New Year! Goodbye 2020, a year no one could have imagined, with our lives and headlines dominated by COVID-19 as...

Fight for Sight to maximise impact by funding solutions-focused research in priority eye conditions

Fight for Sight aims to stop sight loss by funding pioneering research. Rod McNeil takes a look at the Primer Fellowship Awards programme, which provides funding for up to £60,000 for individuals to undertake vision-related research for one year. Among...