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Can retinal layer thickness predict the progression of disability in MS?
This is an observational retrospective cohort study presenting the data of 188 patient diagnoses with multiple sclerosis at two specialist centres. All included patients were adults below the age of 70 years, stable on their disease modifying treatment for at...
Does lower eyelid entropion repair alter corneal topography?
The authors aimed to analyse the corneal morphology before and after advancement of posterior lower eyelid retractors (LERs) alone or in combination with a lateral tarsal strip (LTS) for lower eyelid involutional entropion. Retrospective analysis of 24 consecutive elderly patients...
Treatment and outcomes for Peters anomaly (PA)
The purpose of this study was to evaluate the experience of patients with Peters anomaly (PA) and their treatment results. The study reviewed records of 27 patients (32 eyes); 74% male. Treatment included medical follow-up, optical iridectomy and penetrating keratoplasty...
Progression of macular atrophy on long-term anti-VEGF therapy for AMD
This retrospective study evaluated the progression of macular atrophy in 53 eyes of 53 patients receiving AntiVEGF Therapy for age-related macular degeneration (nAMD), for at least six years. None of the patients had any macular atrophy (MA) at presentation. MA...
Exploring the potential of neurodegenerative disease screening within age-related eye disease research
The authors recruited healthy controls aged between 60 and 75-years-old, previously enrolled into a registry as patients following cataract surgery without age-related macular degeneration (AMD). Exclusion criteria included dense cataract, retinal disease, ocular inflammatory disease, moderate glaucoma, optic neuropathy, cancer,...
Sub-clinical detection methods in multiple sclerosis
Visually symptomatic multiple sclerosis (MS) provides only part of the required information to assist in understanding the disease. Recently, researchers have concentrated their efforts on diagnosing MS cases in the subclinical period. The aim of this paper was to assess...
Risk factors identified for glaucoma progression in paediatric glaucoma suspects
A retrospective case review was conducted of children (<18 years) identified as being glaucoma suspects using common clinical criteria or the Childhood Glaucoma Research Network definition. Exclusion criteria included penetrating ocular trauma, treated ocular hypertension / glaucoma and use of...
Microsporidia-induced stromal keratitis: a new cause of presumed immune stromal (interstitial) keratitis
This is a non-comparative retrospective observational case series from India from 1 October 2020 to 31 January 2021. The inclusion criteria were: (1) presence of nummular / coin shaped lesions with at least one >2mm in size and / presence...
Blood pressure association with primary open angle glaucoma severity
This prospective observational study involved 47 patients diagnosed with primary open angle glaucoma (POAG) examined to investigate their postural blood pressure response and its potential correlation with the severity of glaucomatous optic neuropathy (GON). Participants underwent intraocular pressure and systemic...
Comparison of structural and functional features in primary angle closure and open-angle glaucoma
In this large cross-sectional study, differences in structural and functional damage were assessed among patients with primary open-angle glaucoma (POAG) and primary angle closure glaucoma (PACG) with optical coherence tomography and reliable visual field testing. Two-hundred and eighty-three patients with...
Tumour characteristics influencing visual field outcomes
This retrospective study aimed to explore correlations between pituitary tumour characteristics which influenced visual field changes. Cases of transsphenoidal surgery from a six-year period resulting in a pathologic diagnosis of pituitary adenoma from a single centre were identified. Individuals were...
