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White dot syndromes

It is fair to say that trainees and consultants who are not medical retina specialists are a bit scared of the so called retinal ‘white dot syndromes’. It is easy to understand why this is the case, as almost every...

SOS (Simplified Ophthalmic Statistics) Part 3: Which statistical test should I use (if any)?

P<0.05 is a statement that brings joy to many researchers. Arguably this is because inclusion of such a statement may increase the chance of acceptance for publication. Whilst statisticians and non-statisticians are united in trying to change this culture, cultural...

The fragile p-value

Abdus Samad Ansari explores the limitation of the p-value and the application of the fragility index in clinical trials. Clinical trials and tribulations? The restoration of vision or more purely the gift of sight is an aspect of care that...

An eyeful of independence

Scots will decide this September whether or not Scotland should be an independent sovereign state. “As all key areas of our business are already fully devolved, it’s very much business as usual for us,” noted a spokesperson for Healthcare Improvement...

Gene therapy for inherited retinal disease: the Manchester Ocular Gene Therapy Group MDT service

The authors describe the process set up in Manchester for the optimum delivery and assessment of a new gene therapy treatment for patients with RPE65 IRD. Inherited retinal dystrophies (IRDs) are the second commonest cause of severe visual impairment in...

Glaucoma: 30 years on

Back in 1993, the late and great Barry Cullen FRCS (Cavan born, Dublin trained), the first editor of Eye News, asked me to write an article about the current treatment of chronic open angle glaucoma (COAG). At the time I...

NYU Langone Health performs world’s first whole-eye & partial-face transplant

Landmark whole-eye transplant is a major paradigm shift for potential vision therapies.

Developing community eye care: the GOS package in Scotland

In the second in the series about community eye care in the home nations, Janet Pooley explains how Scotland has developed its services within GOS. The United Kingdom has devolved healthcare; the powers were transferred from Westminster to Scotland and...

Learning from litigation: ocular drug toxicity

Being the subject of litigation is stressful and upsetting. Having to look back over your previous decisions and justify the care you delivered in good faith can be difficult. Sadly, we all live with the sword of Damocles above us...

Cementing a VISION 2020 LINK partnership between Blantyre and Liverpool – building capacity for DR services alongside research

Malawi is a small land-locked country in eastern Africa with a growing population of over 17 million people. About 45% of the population is aged 14 or under; only 5% are aged 60 or over. The gross national income per...

The treachery of images – making sense of OCT imaging

In 1929 Belgian surrealist Rene Magritte produced his painting La Trahison des Images. It depicted an old fashioned pipe for smoking tobacco and underneath were the words “ceci n’est pas une pipe”, this is not a pipe. You may wonder...

SOS (Simplified Ophthalmic Statistics) Part 2: How to summarise your data and why it’s a good idea to do so

Studies involve capturing data. Statistical techniques allow data to be used to answer important research questions. A case series may have data on a handful of subjects but we are now entering the Big Data arena where datasets can be...