You searched for "visual"
Long-term effect of gene therapy on Leber’s congenital amaurosis
After reporting the first successful gene therapy results for RPE65 deficiency in three patients in a brief report in 2008, the same team from London now report the results of 12 patients followed up for three years after transfection. As...
Mitomycin C versus 5-FU as an adjunctive treatment for trabeculectomy
Antifibrotic agents are used during trabeculectomy (TRAB) to improve long-term surgical success by reducing fibrosis of subconjunctival and episcleral tissue. The purpose of this meta-analysis was to directly compare the efficacy and safety of the two most frequently used antifibrotic...
Combined anti-VEGF and PDT for wet AMD
The authors report on a retrospective case series of combined anti-VEGF and photodynamic therapy (PDT) in the treatment of wet age-related macular degeneration (AMD) refractory to anti-VEGF monotherapy alone. The criteria for treatment failure of anti-VEGF monotherapy were persistent subretinal...
Ocular lubrication versus bandage contact lens in recurrent erosion syndrome (RES)
Twenty-nine patients (eight traumatic, five epithelial basement membrane dystrophy, two idiopathic) were randomised using SPSS to either ocular lubricants or bandage contact lenses (BCLs). Only patients previously treated with ocular lubricants were included. Patients with previous surgery, laser treatment, dry...
Cataract surgery in patients with Vogt-Koyanagi-Harada
This retrospective, interventional case series of 286 patients (408 eyes) assessed visual outcome and prognostic factors in patients with Vogt-Koyanagi-Harada (VKH) undergoing cataract surgery between September 2008 and December 2017. Two groups were reviewed. The first group (352 eyes) had...
Does amniotic membrane transplant improve outcomes in chemical injuries?
This single centre, randomised, parallel-controlled clinical trial compared the outcomes of patients with Roper-Hall grade IV ocular chemical injury that had conventional treatment vs. combined medical treatment and amniotic membrane transplantation (AMT). They followed up 60 patients between August 2006...
Lacrimal gland carcinoma outcomes
This is retrospective review of outcomes of lacrimal gland epithelial tumours treated between 1972 and 2014 at Moorfields Eye Hospital. Seventy-nine patients were reported, comprising 53 adenoid cystic carcinomas, 15 primary adenocarcinomas and 11 carcinomas ex-pleomorphic adenoma. The authors compare...
Intracameral sodium hyaluronate for postoperative hypotony after Baerveldt glaucoma implant
This is a retrospective study to examine the effect of 0.1ml of sodium intracameral sodium hyaluronate 1.4% (Healon GV – HGV) in patients who had hypotony (IOP<5mmHg) within three months of having a Baerveldt glaucoma implant (BGI) operation. Hypotony is...
Atrophy and anti-VEGF
The aim of this study was to investigate treatment factors, along with ocular and systemic factors for their association with macular atrophy (MA) incidence in eyes with neovascular age-related macular degeneration (nAMD) treated with anti-VEGF aflibercept or ranibizumab according to...
Mini DMEK for acute hydrops
This is a retrospective analysis of three patients who underwent mini DMEK for massive corneal hydrops in acute keratoconus. DMEK graft was trephined or trimmed according to the size and the shape of the gap in the patient’s Descemet membrane...
Injection of methotrexate into silicone oil-filled eyes for grade C PVR
Methotrexate (MTX) is an antineoplastic antimetabolite with immunosuppressant properties. Folate antagonism is known to contribute to the antiproliferative effects of MTX, and release of adenosine from cells and inhibition of polyamines may explain its anti-inflammatory effects. These activities contribute to...
