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Transcriptomic and regulatory gene associations in open angle glaucoma
The authors report a study utilising a publicly available whole exome sequencing dataset of 28 patients with primary open angle glaucoma (POAG) and seven healthy control patients, and a transcriptomic dataset from the trabecular meshwork of four POAG patients and...
Ocular manifestations of Whipple’s disease
In this retrospective review of 217 patients with Whipple’s disease (WD), the authors reviewed the presentations of those with ocular manifestations. Ocular signs of WD are under recognised, frequently resulting in misdiagnosis and mismanagement. Mayo Data Explorer, a Mayo Clinic...Ellen aims to inspire a future focused on accessibility
Ellen Doherty, 47, who has macular degeneration due to Stargardt’s disease, became one of Scotland’s first Sight Loss Council volunteers earlier this year and is determined to inspire others to make accessibility a priority. Ellen and Callum Lancashire, Engagement Manager,...Informed consent – the Brexit test
The Medical Defence Union (MDU) runs courses on various medicolegal topics. I would guess people only ever attend these courses if they have an exam or an interview approaching as the subject matter is exceedingly dry for clinicians. I myself...The Complainers
There she was. Sitting in the waiting room with her arms crossed, tut-tutting to herself and shaking her head mournfully every few minutes. We gazed at her from a safe distance while one of the nurses confirmed what we already...Vision Care for Homeless People
Vison Care for Homeless People (VCHP) was first established in 2003 with the aim to provide eye tests and glasses free of charge to people living in shelters, hostels or who are sleeping rough. Today, we remain the only national...
Neurotrophic keratitis
The authors present an overview of the aetiology, diagnosis, current and future management options of neurotrophic keratitis. This is a degenerative corneal disease that occurs following the compromise of trigeminal innervation, leading to hypoesthesia and / or anaesthesia. The aetiology...
Case reports of neuro-ophthalmological complications of CIPD
The authors present three cases of neuro-ophthalmological complications of chronic inflammatory demyelinating polyradiculoneuropathy (CIPD). CIPD can lead to prominent nerve hypertrophy which can mimic other forms of neuropathy radiologically. In addition, complications can occur which can cause diagnostic difficulties. All...
Lucentis for pseudophakic CMO
Pseudophakic cystoid macular oedema (CMO) develops angiographically in up to 20-30% after uneventful phacoemulsification. This study aimed to evaluate the potential efficacy and safety of intravitreal ranibizumab in patients with pseudophakic CMO after cataract surgery. Seven eyes were included in...
