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Rebamipide 2% for dry eye

Rebamipide is a quinolinone derivative that has been found to increase mucin production and the number of conjunctival goblet cells. A previous phase two study has shown rebamipide 2% to be better than placebo in improving the ocular surface and...

VDT use and dry eye disease in children

There has been an increase in the amount of work performed using video display terminals. This study compared school children with and without dry eye disease and evaluated the risk factors of dry eye disease and evaluated the risk factors...

Assessment and management of dry eye disease

This paper is an update on the assessment and management of dry eye disease (DED). According to the second International Dry Eye Workshop 2017, “Dry eye is a multifactorial disease of the ocular surface characterised by a loss of homoeostasis...

Topical atorvastatin for dry eye and blepharitis

Dry eye is a very common problem with 20% of the population affected and is frequently associated with blepharitis (DEB), which has an over prevalence of about 40%. The aim of this study was to evaluate a topical atorvastatin formulation...

The impact of conjunctivochalasis on dry eye symptoms and signs

The study aimed to draw a relationship between conjunctivochalasis and dry eye symptoms via a dry eye questionnaire (DEQ5), as well as signs such as tear osmolarity, tear break up time, corneal staining, Schirmer score, meibomian gland dropout, eye lid...

Tear production levels and dry eye disease

Dry eye disease (DED) is multifactorial, caused by an alteration in the quality or quantity of tear film’s three layers. Several tests are available for diagnosis. The aim of this study was to determine if the Schirmer test (ST) could...

No risk of dry eye disease in concomitant strabismus cases

This preliminary assessment of the ocular surface of patients with concomitant strabismus before surgery was undertaken to determine if the presence of strabismus increases the risk of dry eye disease. This was a cross-sectional study of 204 patients with concomitant...

Is there an association between dry eye disease and depression and anxiety?

Dry eye disease is a widespread ocular surface condition (prevalence 5.5-33.7%) that has been previously linked to systemic diseases, such as Sjogren, rheumatoid arthritis and more recently possibly also depression, in small population-based studies. The authors’ aim was to investigate...

Association between diabetes mellitus and dry eye disease

Diabetes mellitus (DM) is currently one of the most prevalent chronic diseases in the United States. It is estimated that 12.3% of Americans suffer from DM. In this study the authors compare between dry eye and diabetes mellitus among a...

Treatment of Sjogren’s Syndrome dry eye in mouse model

Sjogren’s syndrome (SS) is a chronic autoimmune disease characterised by inflammation of the exocrine glands, specifically the salivary and lacrimal glands that produce saliva and tears, respectively. The immune-mediated attack on the salivary and lacrimal glands leads to the development...