Antigoni Koukkoulli

Consultant Ophthalmologist

MBBS, FRCOphth, MSc, MEd, Pantheo Eye Centre, Limassol, Cyprus.

Latest Contribution

Image showing diffuse ganglion cell loss.

Shedding light on Wolfram syndrome: The unveiling of a delayed diagnosis

12 August 2025 | | EYE - Neuro-ophthalmology

Wolfram syndrome 1 (WS1) was first described by Wolfram and Wagener in 1938 and it’s a rare neurodegenerative, progressive disorder, also known as DIDMOAD (diabetes insipidus, diabetes mellitus, optic atrophy, and deafness) [1]. We present an atypical case of WS...

Image showing patient presented several months later with upper and lower lip painless oedema.

Melkersson-Rosenthal syndrome

3 October 2024 | | EYE - Neuro-ophthalmology

Melkersson-Rosenthal syndrome (MRS) is a rare neuro-mucocutaneous disorder which is defined by a triad of orofacial oedema, furrowing of the tongue, and recurrent episodes of facial nerve palsy [1]. Due to the rarity of the disease and inconsistent presentation, MRS...

Acute retinal necrosis presumably caused by Epstein-Barr virus infection

1 October 2015 | | EYE - Cataract, EYE - Cornea, EYE - General, EYE - Glaucoma, EYE - Imaging, EYE - Neuro-ophthalmology, EYE - Oculoplastic, EYE - Oncology, EYE - Orbit, EYE - Paediatrics, EYE - Pathology, EYE - Refractive, EYE - Strabismus, EYE - Vitreo-Retinal

Acute retinal necrosis (ARN) is an uncommon, but serious and potentially blinding condition. ARN is characterised by panuveitis, occlusive vasculopathy and progressive peripheral necrotising retinitis. The diagnosis is clinical but confirmation is sought via aqueous and vitreous sampling. Varicella zoster...