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RPE tears after intravitreal Lucentis

1 February 2017 | | EYE - Vitreo-Retinal
The current hypothesis regarding retinal pigment epithelium (RPE) tears is the contraction and fibrosis in choroidal neovascularisation (CNV) tissue after anti-VEGF therapy can induce rips in the overlying RPE. This South Korean study aimed to identify the association between RPE...

Intravitreal bevacizumab vs. ranibizumab in the treatment of macular oedema due to BRVO

1 June 2016 | | EYE - Paediatrics, EYE - Strabismus
This is a randomised, prospective, non-inferiority trial of 75 patients with macular oedema due to a branch retinal vein occlusion (BRVO) who received intravitreal injections of ranibizumab or bevacizumab after 1:1 block randomisation. This study is to measure the difference...

Retinal pigment epithelium tears

1 June 2016 | | EYE - Vitreo-Retinal
In this paper the authors review the current knowledge of retinal pigment epithelium (RPE) tears. Although rare these can cause loss of visual acuity. They can occur spontaneously in pigment epithelial detachment (PED) due to occult choroidal neovascularisation (CNV), retinal...

Subthreshold micropulse laser treatment in chronic central serous chorioretinopathy

1 February 2016 | | EYE - Vitreo-Retinal
This retrospective study was conducted to assess the treatment of 38 patients of chronic central serous chorioretinopathy with a 577-nm subthreshold micropulse laser (SML) Supra Scan Quantel Medical. Eighteen patients of these had persistent subretinal fluid (SRF) after photodynamic therapy....

Ranibizumab safety in pregnancy

1 December 2018 | | EYE - Vitreo-Retinal
Vascular endothelial growth factor (VEGF) plays a pivotal role during pregnancy, and systemic anti-VEGF administration during this period should thus be avoided. VEGF is expressed in multiple embryonic and foetal tissues during development, with the highest levels found in the...

RPE atrophy onset in treated nAMD

1 October 2019 | | EYE - Vitreo-Retinal
In this study the authors aim to evaluate the role of various factors for the development of retinal pigment epithelium (RPE) atrophy over a period of five years in patients with nAMD. Fifty-two newly diagnosed nAMD patients with complete absence...
Ophthalmologica journal cover image

Evaluation of Optive® in ocular discomfort after anti-VEGF intravitreal injection

1 October 2021 | | EYE - Vitreo-Retinal | Artificial tear, Intravitreal injection therapy, Ocular discomfort, Ocular surface
In this study the authors prospectively evaluated the efficacy of Optive® eye drops after in full, then abbreviation - intravitreal injection (IVT). Patients naïve to IVT were included in the study. No artificial tear treatment was prescribed after the first...

Coming to terms with AI

1 August 2019 | | EYE - Imaging, EYE - Vitreo-Retinal, EYE - Glaucoma, EYE - General
A machine might be called intelligent if its response to questions could convince a person that it was human, a test proposed by Alan Turing in 1950 [1]. The author considers potential applications of artificial intelligence (AI) using machine learning...

A rare neonatal presentation of bilateral dacryocele and choanal atresia

27 October 2021 | | EYE - Oculoplastic, EYE - General
Following a routine pregnancy, a newly delivered baby boy, born at term, was found to have increased work of breathing, stridor and a left medial canthal swelling. The baby required 100% oxygen via a face mask to maintain oxygen saturations....

Quiz Dec/Jan 2023

1 December 2022 | | EYE - General
History A 35-year-old female presented to the emergency eye clinic with an acutely red, painful, photophobic left eye. She was a contact lens-wearer but denied swimming, showering, or sleeping in her lenses. She resided on a farm and worked as...

Insights on medical AI for ophthalmology: an update on current perspectives

3 June 2024 | | EYE - General
Artificial intelligence (AI) has immense promise for revolutionising medical practice. Generative AI is a form of AI in which algorithms are trained on datasets that can be used to generate new content, such as text, images or video based on...

Corneal dystrophies simplified

1 February 2017 | | EYE - Cornea
Based on biomicroscopic and histopathologic features, corneal dystrophies can be broadly classified into epithelial, Bowman’s layer / anterior stromal, stromal, and endothelial dystrophies. Corneal dystrophies are a group of inherited, bilateral, gradually progressing, non- inflammatory conditions caused by accumulation of...